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Slc17a7
Gene Detail
 Symbol
Name
ID
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
MGI:1920211
Synonyms 2900052E22Rik, Vglut1
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:45163921-45176138 bp, + strand
From Ensembl annotation of GRCm38

  12218 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:113454  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 2 zebrafish

Gene Tree: Slc17a7

Human
homologs
Human Homolog SLC17A7, solute carrier family 17 (vesicular glutamate transporter), member 7
NCBI Gene ID 57030
neXtProt AC  NX_Q9P2U7
Human Synonyms  BNPI, VGLUT1
Human Chr (Location)  19q13; chr19:49429398-49441551 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Homozygous mutant mice are small and fail to thrive by 3-4 weeks of age. Abnormal excitatory post synaptic potential and currents.
 
Gene Ontology
(GO)
classifications
All GO classifications: (37 annotations)
Process ion transport, L-glutamate import, ...
Component cell junction, cerebellar mossy fiber, ...
Function inorganic phosphate transmembrane transporter activity, sodium-dependent phosphate transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (54 records)
Data Summary: Results (22)    Tissues (11)    Images (15)
Theiler Stages: 23, 26, 28
Assay TypeResults
Immunohistochemistry 2
RNA in situ 16
Western blot 4
cDNA source data(29)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(33) cDNA(30) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000070570 (Evidence)
Entrez Gene72961 (Evidence)
UniGene255631
DFCITC1579987, TC1622052, TC1676879, TC1698799
DoTSDT.101307992, DT.482191, DT.94130922, DT.94150336, DT.94271713
NIA Mouse Gene IndexU113780
Consensus CDS ProjectCCDS52244.1
International Mouse Knockout Project StatusSlc17a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070570 Ensembl Gene Model | MGI Sequence Detail 12218 C57BL/6J ±  kb
transcript ENSMUST00000085374 Ensembl | MGI Sequence Detail 2939 Not Applicable 
polypeptide ENSMUSP00000082489 Ensembl | MGI Sequence Detail 560 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
Protein Ontology PR:000014963 vesicular glutamate transporter 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206458 Biesemann C, et al., Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO J. 2014 Jan 13;33(2):157-70
All references(113)
Other
accession IDs
MGI:2142059

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory