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Slc17a7
Gene Detail
Symbol

Name
ID
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
MGI:1920211
Synonyms
2900052E22Rik, Vglut1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
29.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:45163921-45176138 bp, + strand
From Ensembl annotation of GRCm38

  12218 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:113454  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: SLC17A7
Gene Tree: Slc17a7

Human
homologs
SLC17A7, solute carrier family 17 (vesicular glutamate transporter), member 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 57030
neXtProt AC: NX_Q9P2U7

Human Synonyms: BNPI, VGLUT1

Human Chr (Location): 19q13; chr19:49429398-49441551 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are small and fail to thrive by 3-4 weeks of age. Abnormal excitatory post synaptic potential and currents.
 
Interactions
Slc17a7 interacts with 221 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (64 records)
Data Summary: Results (69)    Tissues (30)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 9
RNA in situ 51
Western blot 4
RT-PCR 5
cDNA source data(30)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase slc17a7 ; ZFIN slc17a7a    NEW 
Molecular
reagents
All nucleic(35) cDNA(31) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000070570 (Evidence)
Entrez Gene 72961 (Evidence)
UniGene 255631
DFCI TC1676879, TC1698799, TC1622052, TC1579987
DoTS DT.94150336, DT.482191, DT.94130922, DT.101307992, DT.94271713
NIA Mouse Gene Index U113780
Consensus CDS Project CCDS52244.1
International Mouse Phenotyping Consortium Status Slc17a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070570 Ensembl Gene Model | MGI Sequence Detail 12218 C57BL/6J ±  kb
transcript ENSMUST00000085374 Ensembl | MGI Sequence Detail 2939 Not Applicable 
polypeptide ENSMUSP00000082489 Ensembl | MGI Sequence Detail 560 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
Protein Ontology PR:000014963 vesicular glutamate transporter 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:220523 Harris JA, et al., Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits. 2014;8:76
All references(129)
Other
accession IDs
MGI:2142059

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory