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Phykpl
Gene Detail
 Symbol
Name
ID
Phykpl
5-phosphohydroxy-L-lysine phospholyase
MGI:1920197
Synonyms 2900006B13Rik, Agxt2l2
Feature Type protein coding gene
Genetic Map
Chromosome 11
31.08 cM, cytoband B1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:51584757-51604489 bp, + strand
From VEGA annotation of GRCm38

  19733 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75268  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Transaminase_4ab_Lys_Orn
Gene Tree: Phykpl

Human
homologs
Human Homolog PHYKPL, 5-phosphohydroxy-L-lysine phospho-lyase
NCBI Gene ID 85007
neXtProt AC  NX_Q8IUZ5
Human Synonyms  AGXT2L2, PHLU
Human Chr (Location)  5q35.3; chr5:178208474-178232822 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PHYKPL
Alleles
and
phenotypes
All alleles(6) : Targeted(5) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process biological_process
Component mitochondrion
Function catalytic activity, lyase activity, ...
External Resources: FuncBase
Expression
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005604 (Evidence)
Ensembl Gene ModelENSMUSG00000020359 (Evidence)
Entrez Gene72947 (Evidence)
EC4.2.3.134
Consensus CDS ProjectCCDS24653.1
International Mouse Knockout Project StatusPhykpl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005604 VEGA Gene Model | MGI Sequence Detail 19733 C57BL/6J ±  kb
transcript OTTMUST00000090428 VEGA | MGI Sequence Detail 1609 Not Applicable 
polypeptide OTTMUSP00000049607 VEGA | MGI Sequence Detail 468 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(81 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005814 Aminotransferase class-III
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Protein Ontology PR:000003852 alanine--glyoxylate aminotransferase 2-like 2
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory