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Phykpl
Gene Detail
Symbol

Name
ID
Phykpl
5-phosphohydroxy-L-lysine phospholyase
MGI:1920197
Synonyms
2900006B13Rik, Agxt2l2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
31.08 cM, cytoband B1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:51584757-51604489 bp, + strand
From VEGA annotation of GRCm38

  19733 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75268  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: PHYKPL
Protein SuperFamily: Transaminase_4ab_Lys_Orn
Gene Tree: Phykpl

Human
homologs
PHYKPL, 5-phosphohydroxy-L-lysine phospho-lyase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 85007
neXtProt AC: NX_Q8IUZ5

Human Synonyms: AGXT2L2, PHLU

Human Chr (Location): 5q35.3; chr5:178208474-178232822 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PHYKPL

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Phykpl interacts with 215 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process biological_process
Component mitochondrion
Function catalytic activity, identical protein binding, ...
External Resources: FuncBase
Expression
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000005604 (Evidence)
Ensembl Gene Model ENSMUSG00000020359 (Evidence)
Entrez Gene 72947 (Evidence)
EC 4.2.3.134
Consensus CDS Project CCDS24653.1
International Mouse Phenotyping Consortium Status Phykpl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005604 VEGA Gene Model | MGI Sequence Detail 19733 C57BL/6J ±  kb
transcript OTTMUST00000090428 VEGA | MGI Sequence Detail 1609 Not Applicable 
polypeptide OTTMUSP00000049607 VEGA | MGI Sequence Detail 468 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(81 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005814 Aminotransferase class-III
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Protein Ontology PR:000003852 alanine--glyoxylate aminotransferase 2-like 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory