About   Help   FAQ
Hspb11
Gene Detail
 Symbol
Name
ID
Hspb11
heat shock protein family B (small), member 11
MGI:1920188
Synonyms 2900042B11Rik, IFT25
Feature Type protein coding gene
Genetic Map
Chromosome 4
50.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:107253593-107279938 bp, + strand
From VEGA annotation of GRCm38

  26346 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22947  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Hspb11

Human
homologs
Human Homolog HSPB11, heat shock protein family B (small), member 11
NCBI Gene ID 51668
neXtProt AC  NX_Q9Y547
Human Synonyms  C1orf41, HSPCO34, IFT25, PP25
Human Chr (Location)  1p32; chr1:53921561-53946302 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(9) Targeted(3)
 
Homozygous null mice show fetal growth retardation and complete neonatal death due to severe structural heart defects. Omphalocele, polydactyly, left pulmonary isomerism, and skeletal defects such as micrognathia, cleft palate, malaligned sternal vertebrae, and a small rib cage are often observed.
 
Interactions
Hspb11 interacts with 24 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cell adhesion, heart development, ...
Component cell, cell projection, ...
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000008694 (Evidence)
Ensembl Gene ModelENSMUSG00000063172 (Evidence)
Entrez Gene72938 (Evidence)
UniGene21787
DFCITC1584617, TC1668601
DoTSDT.101312845, DT.529270, DT.91347823, DT.97342135
NIA Mouse Gene IndexU004601
Consensus CDS ProjectCCDS18435.1
International Mouse Knockout Project StatusHspb11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008694 VEGA Gene Model | MGI Sequence Detail 26346 C57BL/6J ±  kb
transcript OTTMUST00000019711 VEGA | MGI Sequence Detail 581 Not Applicable 
polypeptide OTTMUSP00000009034 VEGA | MGI Sequence Detail 143 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
InterPro IPR008979 Galactose-binding domain-like
Protein Ontology PR:000008815 heat shock protein beta-11
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:184749 Keady BT, et al., IFT25 Links the Signal-Dependent Movement of Hedgehog Components to Intraflagellar Transport. Dev Cell. 2012 May 15;22(5):940-51
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory