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Hspb11
Gene Detail
Symbol

Name
ID
Hspb11
heat shock protein family B (small), member 11
MGI:1920188
Synonyms
2900042B11Rik, IFT25
Feature Type
protein coding gene
Genetic Map
Chromosome 4
50.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:107253593-107279938 bp, + strand
From VEGA annotation of GRCm38

  26346 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22947  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HSPB11
Gene Tree: Hspb11

Human
homologs
HSPB11, heat shock protein family B (small), member 11
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51668
neXtProt AC: NX_Q9Y547

Human Synonyms: C1orf41, HSPCO34, IFT25, PP25

Human Chr (Location): 1p32; chr1:53921561-53946303 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(9) Targeted(4)
Genomic Mutations involving Hspb11 (1)
Incidental mutations (data from CvDC )
 
Homozygous null mice show fetal growth retardation and complete neonatal death due to severe structural heart defects. Omphalocele, polydactyly, left pulmonary isomerism, and skeletal defects such as micrognathia, cleft palate, malaligned sternal vertebrae, and a small rib cage are often observed.
 
Interactions
Hspb11 interacts with 24 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process heart development, intraciliary transport, ...
Component cell, cell projection, ...
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hspb11    NEW 
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000008694 (Evidence)
Ensembl Gene Model ENSMUSG00000063172 (Evidence)
Entrez Gene 72938 (Evidence)
UniGene 21787
DFCI TC1584617, TC1668601
DoTS DT.101312845, DT.529270, DT.91347823, DT.97342135
NIA Mouse Gene Index U004601
Consensus CDS Project CCDS18435.1
International Mouse Phenotyping Consortium Status Hspb11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008694 VEGA Gene Model | MGI Sequence Detail 26346 C57BL/6J ±  kb
transcript OTTMUST00000019711 VEGA | MGI Sequence Detail 581 Not Applicable 
polypeptide OTTMUSP00000009034 VEGA | MGI Sequence Detail 143 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
InterPro IPR008979 Galactose-binding domain-like
Protein Ontology PR:000008815 heat shock protein beta-11
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:215956 Ishikawa H, et al., TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella. Elife. 2014;3:e01566
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory