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Zdhhc4 Gene Detail
Summary
  • Symbol
    Zdhhc4
  • Name
    zinc finger, DHHC domain containing 4
  • Synonyms
    1810021D01Rik, 2900029I10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920131
    NCBI Gene: 72881
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:143302244-143315007 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 82.08 cM, cytoband G2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    484 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920131
 protein coding gene Chr5:143302244-143315011 (-)
129S1/SvImJ ENSMUSG00200039630
 protein coding gene Chr5:137170424-137183192 (-)
A/J ENSMUSG00195039554
 protein coding gene Chr5:136814877-136827644 (-)
AKR/J ENSMUSG00220021123
 protein coding gene Chr5:136047851-136060617 (-)
BALB/cJ ENSMUSG00180032778
 protein coding gene Chr5:136916914-136929683 (-)
C3H/HeJ ENSMUSG00175036129
 protein coding gene Chr5:138842431-138855198 (-)
C57BL/6NJ ENSMUSG00215032918
 protein coding gene Chr5:136751044-136763811 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027978
 protein coding gene Chr5:136041154-136055058 (-)
CAST/EiJ ENSTCUG00005027624
 protein coding gene Chr5:136198245-136210673 (-)
CBA/J ENSMUSG00210023436
 protein coding gene Chr5:137649271-137662042 (-)
DBA/2J ENSMUSG00185051924
 protein coding gene Chr5:140644121-140656888 (-)
FVB/NJ ENSMUSG00205032881
 protein coding gene Chr5:136468590-136481359 (-)
JF1/MsJ ENSUMUG00000035574
 protein coding gene Chr5:143526160-143538764 (-)
LP/J ENSMUSG00230026893
 protein coding gene Chr5:144774172-144786938 (-)
NOD/ShiLtJ ENSMUSG00190035090
 protein coding gene Chr5:136607388-136620157 (-)
NZO/HlLtJ ENSMUSG00225022829
 protein coding gene Chr5:152241652-152254419 (-)
PWK/PhJ ENSLUMG00010018905
 protein coding gene Chr5:135232123-135244714 (-)
SPRET/EiJ ENSMSPG00010025479
 protein coding gene Chr5:138841825-138853493 (-)
WSB/EiJ ENSIUOG00005031180
 protein coding gene Chr5:139132768-139145498 (-)



Homology
more
  • Human Ortholog
    ZDHHC4, zDHHC palmitoyltransferase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDHHC4, zDHHC palmitoyltransferase 4
  • Synonyms
    ZNF374
  • Links
    NCBI Gene ID: 55146
    UniProt: Q9NPG8

  • Chr Location
    7p22.1; chr7:6577405-6589374 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired fatty acid uptake and impaired adaptive thermogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    606
  • Tissues
    9
  • cDNA Data
    10
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72881 NCBI Gene Model | MGI Sequence Detail 12764 C57BL/6J ±  kb
    transcript NM_001359445 RefSeq | MGI Sequence Detail 1922 C57BL/6  
    polypeptide Q9D6H5 UniProt | EBI | MGI Sequence Detail 343 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1916365
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory