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Mblac2 Gene Detail
Summary
  • Symbol
    Mblac2
  • Name
    metallo-beta-lactamase domain containing 2
  • Synonyms
    2900024O10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920102
    NCBI Gene: 72852
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:81711417-81753275 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 43.68 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920102
protein coding gene Chr13:81711341-81753275 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020789
protein coding gene Chr13:82480584-82518999 (+)
A/J MGP_AJ_G0020745
protein coding gene Chr13:79607097-79652290 (+)
AKR/J MGP_AKRJ_G0020718
protein coding gene Chr13:81960486-82000122 (+)
BALB/cJ MGP_BALBcJ_G0020741
protein coding gene Chr13:80149834-80194673 (+)
C3H/HeJ MGP_C3HHeJ_G0020535
protein coding gene Chr13:81707645-81748714 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021178
protein coding gene Chr13:85159643-85202639 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018746
protein coding gene Chr13:76075601-76108739 (+)
CAST/EiJ MGP_CASTEiJ_G0020053
protein coding gene Chr13:80800611-80841099 (+)
CBA/J MGP_CBAJ_G0020494
protein coding gene Chr13:88396150-88437334 (+)
DBA/2J MGP_DBA2J_G0020619
protein coding gene Chr13:79259371-79294968 (+)
FVB/NJ MGP_FVBNJ_G0020599
protein coding gene Chr13:78344669-78383233 (+)
LP/J MGP_LPJ_G0020692
protein coding gene Chr13:82701494-82740110 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020628
protein coding gene Chr13:87300128-87344010 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021218
protein coding gene Chr13:81382434-81419155 (+)
PWK/PhJ MGP_PWKPhJ_G0019806
protein coding gene Chr13:78175144-78211424 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019629
protein coding gene Chr13:77621045-77660023 (+)
WSB/EiJ MGP_WSBEiJ_G0020110
protein coding gene Chr13:81811167-81849370 (+)



Homology
more
  • Human Ortholog
    MBLAC2, metallo-beta-lactamase domain containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MBLAC2, metallo-beta-lactamase domain containing 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 153364
    neXtProt AC: NX_Q68D91
    UniProt: Q68D91

  • Chr Location
    5q14.3; chr5:90458203-90474768 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 15174
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MBLAC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Mblac2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72852 NCBI Gene Model | MGI Sequence Detail 41859 C57BL/6J ±  kb
transcript NM_028372 RefSeq | MGI Sequence Detail 3881 C57BL/6  
polypeptide Q8BL86 UniProt | EBI | MGI Sequence Detail 279 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory