About   Help   FAQ
Ubash3b Gene Detail
Summary
  • Symbol
    Ubash3b
  • Name
    ubiquitin associated and SH3 domain containing, B
  • Synonyms
    2810457I06Rik, Sts-1, TULA-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920078
    NCBI Gene: 72828
  • Gene Overview
    MyGene.info: UBASH3B
Location & Maps
more
  • Sequence Map
    Chr9:41011098-41161697 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      150600 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 21.84 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    UBASH3B, ubiquitin associated and SH3 domain containing B
  • Vertebrate Orthologs
    11
  • Human Ortholog
    UBASH3B, ubiquitin associated and SH3 domain containing B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    p70, STS1, STS-1, TULA2, TULA-2
  • Links
    NCBI Gene ID: 84959
    neXtProt AC: NX_Q8TF42
    UniProt: Q8TF42

  • Chr Location
    11q24.1; chr11:122655690-122814479 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    12 phenotype references
Mice homozygous for a knock-out allele are viable, fertile, developmentally normal, and do not display any obvious phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025903 VEGA Gene Model | MGI Sequence Detail 150600 C57BL/6J ±  kb
transcript OTTMUST00000063835 VEGA | MGI Sequence Detail 6354 Not Applicable  
polypeptide OTTMUSP00000031634 VEGA | MGI Sequence Detail 638 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2098 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143364
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:237276 Reppschlager K, et al., TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk. J Biol Chem. 2016 Oct 21;291(43):22427-22441

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory