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Ubash3b Gene Detail
Summary
  • Symbol
    Ubash3b
  • Name
    ubiquitin associated and SH3 domain containing, B
  • Synonyms
    2810457I06Rik, Sts-1, TULA-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920078
    NCBI Gene: 72828
  • Gene Overview
    MyGene.info: UBASH3B
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:41011098-41161697 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 21.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2098 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920078
protein coding gene Chr9:41010760-41161697 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034674
protein coding gene Chr9:39262894-39414493 (-)
A/J MGP_AJ_G0034654
protein coding gene Chr9:38247037-38400848 (-)
AKR/J MGP_AKRJ_G0034580
protein coding gene Chr9:38966974-39122295 (-)
BALB/cJ MGP_BALBcJ_G0034645
protein coding gene Chr9:37988852-38141205 (-)
C3H/HeJ MGP_C3HHeJ_G0034356
protein coding gene Chr9:39491938-39647473 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035168
protein coding gene Chr9:40506858-40664441 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032081
protein coding gene Chr9:37872617-38024493 (-)
CAST/EiJ MGP_CASTEiJ_G0033679
protein coding gene Chr9:39226151-39381717 (-)
CBA/J MGP_CBAJ_G0034329
protein coding gene Chr9:41893915-42060615 (-)
DBA/2J MGP_DBA2J_G0034488
protein coding gene Chr9:38179569-38332643 (-)
FVB/NJ MGP_FVBNJ_G0034428
protein coding gene Chr9:37409175-37559798 (-)
LP/J MGP_LPJ_G0034569
protein coding gene Chr9:39534077-39690615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034472
protein coding gene Chr9:43954984-44029050 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035187
protein coding gene Chr9:38890786-39048691 (-)
PWK/PhJ MGP_PWKPhJ_G0033384
protein coding gene Chr9:37996081-38146263 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033220
protein coding gene Chr9:39123415-39285463 (-)
WSB/EiJ MGP_WSBEiJ_G0033792
protein coding gene Chr9:38918343-39073415 (-)



Homology
more
  • Human Ortholog
    UBASH3B, ubiquitin associated and SH3 domain containing B
  • Vertebrate Orthologs
    11
  • Human Ortholog
    UBASH3B, ubiquitin associated and SH3 domain containing B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    p70, STS1, STS-1, TULA2, TULA-2
  • Links
    NCBI Gene ID: 84959
    neXtProt AC: NX_Q8TF42
    UniProt: Q8TF42

  • Chr Location
    11q24.1; chr11:122655690-122814479 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    12 phenotype references
Mice homozygous for a knock-out allele are viable, fertile, developmentally normal, and do not display any obvious phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032020 Ensembl Gene Model | MGI Sequence Detail 150600 C57BL/6J ±  kb
transcript ENSMUST00000044155 Ensembl | MGI Sequence Detail 6354 Not Applicable  
polypeptide ENSMUSP00000043865 Ensembl | MGI Sequence Detail 638 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143364
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:248701 Zhou Y, et al., TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcgammaRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice. Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2315-2323

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory