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Ttc19
Gene Detail
 Symbol
Name
ID
Ttc19
tetratricopeptide repeat domain 19
MGI:1920045
Synonyms 2010204O13Rik, 2810460C24Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
38.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:62281473-62328451 bp, + strand
From VEGA annotation of GRCm38

  46979 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9831  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ttc19

Human
homologs
Human Homolog TTC19, tetratricopeptide repeat domain 19
NCBI Gene ID 54902
neXtProt AC  NX_Q6DKK2
Human Synonyms  2010204O13Rik, MC3DN2
Human Chr (Location)  17p12; chr17:15999380-16029409 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TTC19
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ttc19 interacts with 307 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process mitochondrial respiratory chain complex III assembly
Component membrane, mitochondrial inner membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (5)    Images (19)
Theiler Stages: 17, 23
Assay TypeResults
RNA in situ 29
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005850 (Evidence)
Ensembl Gene ModelENSMUSG00000042298 (Evidence)
Entrez Gene72795 (Evidence)
DFCITC1580369, TC1588154, TC1599424
DoTSDT.101373869, DT.523805, DT.530561, DT.55140895
NIA Mouse Gene IndexU012731
Consensus CDS ProjectCCDS36177.1, CCDS48817.1
International Mouse Knockout Project StatusTtc19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005850 VEGA Gene Model | MGI Sequence Detail 46979 C57BL/6J ±  kb
transcript OTTMUST00000013013 VEGA | MGI Sequence Detail 3410 Not Applicable 
polypeptide OTTMUSP00000006049 VEGA | MGI Sequence Detail 365 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(9) UniProt(3)
Polymorphisms SNPs within 2kb(204 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR013026 Tetratricopeptide repeat-containing domain
InterPro IPR013105 Tetratricopeptide TPR2
Protein Ontology PR:000029831 tetratricopeptide repeat protein 19, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173130 Ghezzi D, et al., Mutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and flies. Nat Genet. 2011 Mar;43(3):259-63
All references(30)
Other
accession IDs
MGI:1923943, MGI:2144210

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory