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Sass6
Gene Detail
Symbol

Name
ID
Sass6
spindle assembly 6 homolog (C. elegans)
MGI:1920026
Synonyms
2810453L12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
50.40 cM, cytoband G2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:116595008-116630984 bp, + strand
From Ensembl annotation of GRCm38

  35977 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45668  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SASS6
Gene Tree: Sass6

Human
homologs
SASS6, spindle assembly 6 homolog (C. elegans)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 163786
neXtProt AC: NX_Q6UVJ0

Human Synonyms: MCPH14, SAS6, SAS-6

Human Chr (Location): 1p21.2; chr1:100083544-100133095 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SASS6

Mutations,
alleles, and
phenotypes
All mutations/alleles(38) : Gene trapped(36) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Sass6 interacts with 316 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell cycle, centriole replication, ...
Component centriole, centrosome, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (90)    Tissues (7)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 90
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sass6, sass6.2 ; ZFIN sass6    NEW 
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000027959 (Evidence)
Entrez Gene 72776 (Evidence)
UniGene 440836
DFCI TC1650812, TC1584179
NIA Mouse Gene Index U003773
Consensus CDS Project CCDS17789.1
International Mouse Phenotyping Consortium Status Sass6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027959 Ensembl Gene Model | MGI Sequence Detail 35977 C57BL/6J ±  kb
transcript ENSMUST00000029571 Ensembl | MGI Sequence Detail 4241 Not Applicable 
polypeptide ENSMUSP00000029571 Ensembl | MGI Sequence Detail 654 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(10) UniProt(2)
Polymorphisms
SNPs within 2kb(262 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000014465 spindle assembly abnormal protein 6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208267 Kobayashi T, et al., The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. J Cell Biol. 2014 Jan 20;204(2):215-29
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory