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Tmem216 Gene Detail
Summary
  • Symbol
    Tmem216
  • Name
    transmembrane protein 216
  • Synonyms
    1110017C22Rik, 2810441K11Rik, 4921533J23Rik, A930021F15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920020
    NCBI Gene: 68642
Location & Maps
more
  • Sequence Map
    Chr19:10533865-10556238 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22374 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TMEM216, transmembrane protein 216
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM216, transmembrane protein 216
    Orthology source: HomoloGene
  • Synonyms
    HSPC244
  • Links
    NCBI Gene ID: 51259
    neXtProt AC: NX_Q9P0N5

  • Chr Location
    11q13.1; chr11:61391687-61398863 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human TMEM216 associations

Human Disease Mouse Models
       Joubert Syndrome 2; JBTS2   OMIM: 608091
Meckel Syndrome, Type 2; MKS2   OMIM: 603194
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    2
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033090 VEGA Gene Model | MGI Sequence Detail 22374 C57BL/6J ±  kb
transcript OTTMUST00000082658 VEGA | MGI Sequence Detail 927 Not Applicable  
polypeptide OTTMUSP00000044339 VEGA | MGI Sequence Detail 141 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    121 from dbSNP Build 137
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030393 transmembrane protein 216
  • InterPro Domains
    IPR019184 Uncharacterised protein family, transmembrane-17
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915892, MGI:1918182, MGI:1924512, MGI:2147568
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:176174 Garcia-Gonzalo FR, et al., A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Aug;43(8):776-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory