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Hdhd3 Gene Detail
Summary
  • Symbol
    Hdhd3
  • Name
    haloacid dehalogenase-like hydrolase domain containing 3
  • Synonyms
    2810435D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919998
    NCBI Gene: 72748
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62417291-62420437 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 33.16 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    21
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919998
 protein coding gene Chr4:62417245-62421704 (-)
129S1/SvImJ ENSMUSG00200002434
 protein coding gene Chr4:57404411-57407679 (-)
A/J ENSMUSG00195008186
 protein coding gene Chr4:57991846-57995114 (-)
AKR/J ENSMUSG00220005517
 protein coding gene Chr4:57796218-57799486 (-)
BALB/cJ ENSMUSG00180028612
 protein coding gene Chr4:56973800-56977068 (-)
BALB/cJ ENSMUSG00180028490
 protein coding gene Chr4:56944862-56948131 (-)
C3H/HeJ ENSMUSG00175021171
 protein coding gene Chr4:57742163-57745431 (-)
C57BL/6NJ ENSMUSG00215023718
 protein coding gene Chr4:57812297-57815565 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026082
 protein coding gene Chr4:56546598-56551060 (-)
CAST/EiJ ENSTCUG00005007846
 protein coding gene Chr4:57560007-57563279 (-)
CBA/J ENSMUSG00210005140
 protein coding gene Chr4:57478357-57481625 (-)
DBA/2J ENSMUSG00185016870
 protein coding gene Chr4:57895004-57898272 (-)
DBA/2J ENSMUSG00185016609
 protein coding gene Chr4:57866075-57869343 (-)
FVB/NJ ENSMUSG00205017641
 protein coding gene Chr4:56193876-56197143 (-)
JF1/MsJ ENSUMUG00000016139
 protein coding gene Chr4:58550050-58553313 (-)
LP/J ENSMUSG00230011006
 protein coding gene Chr4:61385432-61388700 (-)
NOD/ShiLtJ ENSMUSG00190030994
 protein coding gene Chr4:56900450-56903715 (-)
NZO/HlLtJ ENSMUSG00225012648
 protein coding gene Chr4:66413711-66416979 (-)
PWK/PhJ ENSLUMG00010007055
 protein coding gene Chr4:56168245-56171507 (-)
SPRET/EiJ ENSMSPG00010028026
 protein coding gene Chr4:57438989-57442709 (-)
WSB/EiJ ENSIUOG00005019642
 protein coding gene Chr4:57223510-57226775 (-)



Homology
more
  • Human Ortholog
    HDHD3, haloacid dehalogenase like hydrolase domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HDHD3, haloacid dehalogenase like hydrolase domain containing 3
  • Synonyms
    2810435D12Rik, C9orf158
  • Links
    NCBI Gene ID: 81932
    UniProt: Q9BSH5

  • Chr Location
    9q32; chr9:113373416-113377473 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    36
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72748 NCBI Gene Model | MGI Sequence Detail 3147 C57BL/6J ±  kb
transcript NM_024257 RefSeq | MGI Sequence Detail 1098 Not Specified  
polypeptide Q9CYW4 UniProt | EBI | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032138 haloacid dehalogenase-like hydrolase domain-containing protein 3
    (term hierarchy)
  • InterPro Domains
    IPR006439 HAD hydrolase, subfamily IA
    IPR051828 HAD-like hydrolase domain-containing protein
    IPR036412 HAD-like superfamily
    IPR023214 HAD superfamily
    IPR011949 HAD-superfamily hydrolase, subfamily IA, REG-2-like
    IPR044924 HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory