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Tmx1 Gene Detail
Summary
  • Symbol
    Tmx1
  • Name
    thioredoxin-related transmembrane protein 1
  • Synonyms
    2810425A04Rik, Txndc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919986
    NCBI Gene: 72736
  • Gene Overview
    MyGene.info: TMX1
Location & Maps
more
  • Sequence Map
    Chr12:70453095-70468040 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      14946 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 29.13 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMX1, thioredoxin related transmembrane protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMX1, thioredoxin related transmembrane protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PDIA11, TMX, TXNDC, TXNDC1
  • Links
    NCBI Gene ID: 81542
    neXtProt AC: NX_Q9H3N1
    UniProt: Q9H3N1

  • Chr Location
    14q22.1; chr14:51240168-51257655 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 12482
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMX1
  • Gene Tree
    Tmx1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
No notable phenotype was detected in a high-throughput screen of homozygous mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    10
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034933 VEGA Gene Model | MGI Sequence Detail 14946 C57BL/6J ±  kb
transcript OTTMUST00000088824 VEGA | MGI Sequence Detail 2795 Not Applicable  
polypeptide OTTMUSP00000048463 VEGA | MGI Sequence Detail 278 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    142 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144841
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/12/2017
MGI 6.10 		The Jackson Laboratory