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Tbcc Gene Detail
Summary
  • Symbol
    Tbcc
  • Name
    tubulin-specific chaperone C
  • Synonyms
    2810055C19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919976
    NCBI Gene: 72726
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46890684-46891847 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919976
protein coding gene Chr17:46890621-46892463 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023837
protein coding gene Chr17:48001017-48002859 (+)
A/J MGP_AJ_G0023795
protein coding gene Chr17:46834368-46836210 (+)
AKR/J MGP_AKRJ_G0023766
protein coding gene Chr17:47190490-47192332 (+)
BALB/cJ MGP_BALBcJ_G0023799
protein coding gene Chr17:46731729-46733571 (+)
C3H/HeJ MGP_C3HHeJ_G0023562
protein coding gene Chr17:47934834-47936676 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024242
protein coding gene Chr17:50049635-50051477 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021692
protein coding gene Chr17:43600109-43601867 (+)
CAST/EiJ MGP_CASTEiJ_G0023044
protein coding gene Chr17:48033136-48034978 (+)
CBA/J MGP_CBAJ_G0023539
protein coding gene Chr17:51865373-51867215 (+)
DBA/2J MGP_DBA2J_G0023665
protein coding gene Chr17:45594905-45596747 (+)
FVB/NJ MGP_FVBNJ_G0023632
protein coding gene Chr17:45226705-45228547 (+)
LP/J MGP_LPJ_G0023746
protein coding gene Chr17:48669304-48671146 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023661
protein coding gene Chr17:51390908-51392750 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024287
protein coding gene Chr17:47552532-47554374 (+)
PWK/PhJ MGP_PWKPhJ_G0022788
protein coding gene Chr17:44941751-44943593 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022604
protein coding gene Chr17:44442550-44444335 (+)
WSB/EiJ MGP_WSBEiJ_G0023109
protein coding gene Chr17:48120762-48122604 (+)



Homology
more
  • Human Ortholog
    TBCC, tubulin folding cofactor C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBCC, tubulin folding cofactor C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CFC
  • Links
    NCBI Gene ID: 6903
    neXtProt AC: NX_Q15814
    UniProt: Q15814

  • Chr Location
    6p21.1; chr6:42744496-42746146 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036430 Ensembl Gene Model | MGI Sequence Detail 1164 C57BL/6J ±  kb
transcript ENSMUST00000040434 Ensembl | MGI Sequence Detail 1164 Not Applicable  
polypeptide ENSMUSP00000048696 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR006599 CARP motif
    IPR017901 C-CAP/cofactor C-like domain
    IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal
    IPR038397 TBCC, N-terminal domain superfamily
    IPR012945 Tubulin binding cofactor C-like domain
    IPR027684 Tubulin-specific chaperone C
    IPR031925 Tubulin-specific chaperone C, N-terminal
Molecular
Reagents
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  • All nucleic 42
    cDNA 42

    Microarray probesets 5
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory