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Lime1
Gene Detail
Symbol

Name
ID
Lime1
Lck interacting transmembrane adaptor 1
MGI:1919949
Synonyms
2810038K19Rik, LIME
Feature Type
protein coding gene
Genetic Map
Chromosome 2
103.63 cM, cytoband H4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:181380078-181383628 bp, + strand
From VEGA annotation of GRCm38

  3551 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56785  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: LIME1
Gene Tree: Lime1

Human
homologs
LIME1, Lck interacting transmembrane adaptor 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 54923
neXtProt AC: NX_Q9H400

Human Synonyms: dJ583P15.4, LIME

Human Chr (Location): 20q13.3; chr20:63736626-63739107 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from CvDC )
 
Mice homozygous for a targeted null allele exhibit no detectable abnormalities in the development and function of B and T cells.
 
Interactions
Lime1 interacts with 31 markers (Mir125a, Mir125b-1, Mir125b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process B cell receptor signaling pathway, immune system process, ...
Component B cell receptor complex, extracellular space, ...
Function protein binding, protein kinase binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (51)    Tissues (6)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 51
cDNA source data(53)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(53) cDNA(53)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000016651 (Evidence)
Ensembl Gene Model ENSMUSG00000090077 (Evidence)
Entrez Gene 72699 (Evidence)
UniGene 440138
DFCI TC1579074
Consensus CDS Project CCDS17211.1
International Mouse Phenotyping Consortium Status Lime1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016651 VEGA Gene Model | MGI Sequence Detail 3551 C57BL/6J ±  kb
transcript OTTMUST00000040298 VEGA | MGI Sequence Detail 1959 Not Applicable 
polypeptide OTTMUSP00000018005 VEGA | MGI Sequence Detail 269 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(29 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026072 Lck-interacting transmembrane adapter 1
Protein Ontology PR:000009815 lck-interacting transmembrane adapter 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177766 Lindquist S, et al., Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation. PLoS One. 2011;6(9):e23978
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory