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Zcchc12 Gene Detail
Summary
  • Symbol
    Zcchc12
  • Name
    zinc finger, CCHC domain containing 12
  • Synonyms
    2810028A01Rik, Sizn1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919943
    NCBI Gene: 72693
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:35459557-35462811 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 20.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919943
 protein coding gene ChrX:35459553-35462817 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035617
 protein coding gene ChrX:31091938-31097797 (+)
A/J MGP_AJ_G0035594
 protein coding gene ChrX:31193590-31196881 (+)
AKR/J MGP_AKRJ_G0035527
 protein coding gene ChrX:31839045-31843078 (+)
BALB/cJ MGP_BALBcJ_G0035587
 protein coding gene ChrX:30926298-30929466 (+)
C3H/HeJ MGP_C3HHeJ_G0035305
 protein coding gene ChrX:31422375-31427639 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036123
 protein coding gene ChrX:31711098-31716382 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032985
 protein coding gene ChrX:29335700-29339000 (+)
CAST/EiJ MGP_CASTEiJ_G0034596
 protein coding gene ChrX:19573513-19576817 (+)
CBA/J MGP_CBAJ_G0035274
 protein coding gene ChrX:32567566-32572293 (+)
DBA/2J MGP_DBA2J_G0035426
 protein coding gene ChrX:31016602-31020068 (+)
FVB/NJ MGP_FVBNJ_G0035372
 protein coding gene ChrX:30772262-30776067 (+)
LP/J MGP_LPJ_G0035508
 protein coding gene ChrX:31456796-31460505 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035416
 protein coding gene ChrX:33030862-33034590 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036130
 protein coding gene ChrX:31062557-31066579 (+)
PWK/PhJ MGP_PWKPhJ_G0034297
 protein coding gene ChrX:19073402-19076590 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034138
 protein coding gene ChrX:20065594-20068876 (+)
WSB/EiJ MGP_WSBEiJ_G0034731
 protein coding gene ChrX:30870525-30875102 (+)



Homology
more
  • Human Ortholog
    ZCCHC12, zinc finger CCHC-type containing 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZCCHC12, zinc finger CCHC-type containing 12
  • Synonyms
    PNMA7A, SIZN, SIZN1
  • Links
    NCBI Gene ID: 170261
    neXtProt AC: NX_Q6PEW1
    UniProt: Q6PEW1

  • Chr Location
    Xq24; chrX:118823824-118826968 (+)  GRCh38
  • Human Ortholog
    ZCCHC18, zinc finger CCHC-type containing 18
  • Synonyms
    PNMA7B, SIZN2
  • Links
    NCBI Gene ID: 644353
    neXtProt AC: NX_P0CG32
    UniProt: P0CG32

  • Chr Location
    Xq22.2; chrX:104112131-104115842 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1071
  • Tissues
    80
  • cDNA Data
    29
  • Literature Summary
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036699 Ensembl Gene Model | MGI Sequence Detail 3255 C57BL/6J ±  kb
transcript ENSMUST00000115258 Ensembl | MGI Sequence Detail 2181 Not Applicable  
polypeptide ENSMUSP00000110913 Ensembl | MGI Sequence Detail 402 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 29
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147978
References
more
  • Summaries
    All 42
    Developmental Gene Expression 16
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:338299 Xing L, et al., Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice. Cell Rep. 2023 Jun 28;42(7):112706
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory