Adipor1
Gene Detail

Symbol Name ID

Adipor1 adiponectin receptor 1 MGI:1919924

Synonyms

2810031L11Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 1

58.22 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:134415378-134433351 bp, + strand From VEGA annotation of GRCm38   17974 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Adipor1 ± 2 cM)

Protein SuperFamily: membrane receptor, ADIPOR type
Gene Tree: Adipor1

Human ortholog

ADIPOR1 adiponectin receptor 1 NCBI Gene ID 51094
Human Synonyms: ACDCR1, CGI45, PAQR1, TESBP1A
Human Chr1:202909960-202927700 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(39) : Targeted(5) Gene trapped(34)
 

Mice homozygous for a targeted allele exhibit abnormal homeostasis and adipose tissue morphology.

 

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	adiponectin-mediated signaling pathway, fatty acid metabolic process, ...
Component	integral to membrane, membrane, ...
Function	hormone binding, identical protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (192)    Tissues (113)    Images (35)
Theiler Stages: 20, 23, 24, 26, 28

Assay Type	Results
RNA in situ	102
In situ reporter (knock in)	52
RT-PCR	38

cDNA source data(222)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(225) cDNA(223) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000021808 (Evidence)
Ensembl Gene Model	ENSMUSG00000026457 (Evidence)
Entrez Gene	72674 (Evidence)
UniGene	259976
DFCI	TC1573419, TC1604997, TC1648762, TC1671751
DoTS	DT.494071, DT.525608, DT.55282574, DT.94226653
NIA Mouse Gene Index	U042208
Consensus CDS Project	CCDS15309.1
International Mouse Knockout Project Status	Adipor1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021808	VEGA Gene Model | MGI Sequence Detail	17974	C57BL/6J
transcript	OTTMUST00000051762	VEGA | MGI Sequence Detail	3123	Not Applicable
polypeptide	OTTMUSP00000024419	VEGA | MGI Sequence Detail	375	Not Applicable

All sequences(71) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(66 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004254	Hly-III-related
Protein Ontology	PR:000003778	adiponectin receptor protein 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:172246 Awazawa M, et al., Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab. 2011 Apr 6;13(4):401-12
All references(52)