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Eme2 Gene Detail
Summary
  • Symbol
    Eme2
  • Name
    essential meiotic structure-specific endonuclease subunit 2
  • Synonyms
    2810013J18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919889
    NCBI Gene: 193838
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24892152-24895087 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    41 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919889
protein coding gene Chr17:24888486-24895087 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023329
protein coding gene Chr17:23913907-23920418 (-)
A/J MGP_AJ_G0023289
protein coding gene Chr17:23250696-23257207 (-)
AKR/J MGP_AKRJ_G0023256
protein coding gene Chr17:23339195-23345706 (-)
BALB/cJ MGP_BALBcJ_G0023294
protein coding gene Chr17:23451161-23457749 (-)
C3H/HeJ MGP_C3HHeJ_G0023054
protein coding gene Chr17:23703793-23711044 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023737
protein coding gene Chr17:24976796-24983397 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021212
protein coding gene Chr17:20710934-20717440 (-)
CAST/EiJ MGP_CASTEiJ_G0022556
protein coding gene Chr17:23559073-23565584 (-)
CBA/J MGP_CBAJ_G0023030
protein coding gene Chr17:25818083-25827807 (-)
DBA/2J MGP_DBA2J_G0023159
protein coding gene Chr17:22843359-22850044 (-)
FVB/NJ MGP_FVBNJ_G0023129
protein coding gene Chr17:22563890-22570401 (-)
LP/J MGP_LPJ_G0023236
protein coding gene Chr17:24219170-24225681 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023148
protein coding gene Chr17:25510584-25517095 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023775
protein coding gene Chr17:23623700-23630211 (-)
PWK/PhJ MGP_PWKPhJ_G0022305
protein coding gene Chr17:21598754-21605359 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022123
protein coding gene Chr17:21687979-21694513 (-)
WSB/EiJ MGP_WSBEiJ_G0022619
protein coding gene Chr17:23696335-23702780 (-)



Homology
more
  • Human Ortholog
    EME2, essential meiotic structure-specific endonuclease subunit 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EME2, essential meiotic structure-specific endonuclease subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    gs125, SLX2B
  • Links
    NCBI Gene ID: 197342
    neXtProt AC: NX_A4GXA9
    UniProt: A4GXA9

  • Chr Location
    16p13.3; chr16:1773222-1776714 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19180
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EME2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 193838 NCBI Gene Model | MGI Sequence Detail 2936 C57BL/6J ±  kb
transcript NM_001163102 RefSeq | MGI Sequence Detail 1521 C57BL/6  
polypeptide Q56A04 UniProt | EBI | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 19
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory