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Lins1 Gene Detail
Summary
  • Symbol
    Lins1
  • Name
    lines homolog 1
  • Synonyms
    2700083B01Rik, Lins, Wins2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919885
    NCBI Gene: 72635
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:66689889-66717256 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 36.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    293 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919885
protein coding gene Chr7:66689766-66717256 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032354
protein coding gene Chr7:67923153-67950751 (+)
A/J MGP_AJ_G0032333
protein coding gene Chr7:66527380-66554300 (+)
AKR/J MGP_AKRJ_G0032269
protein coding gene Chr7:67943154-67971126 (+)
BALB/cJ MGP_BALBcJ_G0032345
protein coding gene Chr7:66267757-66295082 (+)
C3H/HeJ MGP_C3HHeJ_G0032058
protein coding gene Chr7:68614073-68641328 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032837
protein coding gene Chr7:70835499-70867071 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029844
protein coding gene Chr7:69422829-69449148 (+)
CAST/EiJ MGP_CASTEiJ_G0031386
protein coding gene Chr7:59296176-59328273 (+)
CBA/J MGP_CBAJ_G0032024
protein coding gene Chr7:73050859-73079827 (+)
DBA/2J MGP_DBA2J_G0032179
protein coding gene Chr7:65248985-65278142 (+)
FVB/NJ MGP_FVBNJ_G0032134
protein coding gene Chr7:65375474-65402642 (+)
LP/J MGP_LPJ_G0032260
protein coding gene Chr7:69140273-69174654 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032171
protein coding gene Chr7:73291214-73320131 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032855
protein coding gene Chr7:67296038-67326873 (+)
PWK/PhJ MGP_PWKPhJ_G0031106
protein coding gene Chr7:58290967-58320207 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030947
protein coding gene Chr7:54336067-54367872 (+)
WSB/EiJ MGP_WSBEiJ_G0031504
protein coding gene Chr7:67641277-67672161 (+)



Homology
more
  • Human Ortholog
    LINS1, lines homolog 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LINS1, lines homolog 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LINS, MRT27, WINS1
  • Links
    NCBI Gene ID: 55180
    neXtProt AC: NX_Q8NG48
    UniProt: Q8NG48

  • Chr Location
    15q26.3; chr15:100566914-100602440 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10034
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LINS1
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human LINS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053091 Ensembl Gene Model | MGI Sequence Detail 27368 C57BL/6J ±  kb
transcript ENSMUST00000121777 Ensembl | MGI Sequence Detail 2729 Not Applicable  
polypeptide ENSMUSP00000112404 Ensembl | MGI Sequence Detail 764 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142255
References
more
  • Summaries
    All 39
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory