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Hpf1 Gene Detail
Summary
  • Symbol
    Hpf1
  • Name
    histone PARylation factor 1
  • Synonyms
    2700029M09Rik, C230006B22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919862
    NCBI Gene: 72612
Location & Maps
more
  • Sequence Map
    Chr8:60890418-60907580 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17163 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 30.90 cM, cytoband B3.2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HPF1, histone PARylation factor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HPF1, histone PARylation factor 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C4orf27
  • Links
    NCBI Gene ID: 54969
    neXtProt AC: NX_Q9NWY4

  • Chr Location
    4q33; chr4:169729468-169757942 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 32374
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: HPF1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Genomic Mutations
    1 involving Hpf1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031399 VEGA Gene Model | MGI Sequence Detail 17163 C57BL/6J ±  kb
transcript OTTMUST00000077801 VEGA | MGI Sequence Detail 1191 Not Applicable  
polypeptide OTTMUSP00000041229 VEGA | MGI Sequence Detail 346 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR019361 Protein of unknown function DUF2228, C2H2, APLF-like
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444303
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory