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Usp13 Gene Detail
Summary
  • Symbol
    Usp13
  • Name
    ubiquitin specific peptidase 13 (isopeptidase T-3)
  • Synonyms
    2700071E21Rik, IsoT-3, ISOT3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919857
    NCBI Gene: 72607
  • Gene Overview
    MyGene.info: USP13
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:32817546-32938071 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 15.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    912 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919857
protein coding gene Chr3:32817017-32938075 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027144
protein coding gene Chr3:30442316-30568707 (+)
A/J MGP_AJ_G0027104
protein coding gene Chr3:30011458-30136645 (+)
AKR/J MGP_AKRJ_G0027073
protein coding gene Chr3:30482843-30617103 (+)
BALB/cJ MGP_BALBcJ_G0027116
protein coding gene Chr3:29658613-29778854 (+)
C3H/HeJ MGP_C3HHeJ_G0026859
protein coding gene Chr3:30506384-30643640 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027562
protein coding gene Chr3:31956024-32087786 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024923
protein coding gene Chr3:27808010-27922669 (+)
CAST/EiJ MGP_CASTEiJ_G0026312
protein coding gene Chr3:30373412-30495523 (+)
CBA/J MGP_CBAJ_G0026836
protein coding gene Chr3:32818871-32958478 (+)
DBA/2J MGP_DBA2J_G0026970
protein coding gene Chr3:29472731-29598721 (+)
FVB/NJ MGP_FVBNJ_G0026938
protein coding gene Chr3:28930156-29052322 (+)
LP/J MGP_LPJ_G0027082
protein coding gene Chr3:31210779-31337444 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026958
protein coding gene Chr3:35303858-35440548 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027621
protein coding gene Chr3:30274299-30410659 (+)
PWK/PhJ MGP_PWKPhJ_G0026045
protein coding gene Chr3:29008969-29137049 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025857
protein coding gene Chr3:29697050-29836144 (+)
WSB/EiJ MGP_WSBEiJ_G0026386
protein coding gene Chr3:30293550-30418980 (+)



Homology
more
  • Human Ortholog
    USP13, ubiquitin specific peptidase 13
  • Vertebrate Orthologs
    10
  • Human Ortholog
    USP13, ubiquitin specific peptidase 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IsoT-3, ISOT3
  • Links
    NCBI Gene ID: 8975
    neXtProt AC: NX_Q92995
    UniProt: Q92995

  • Chr Location
    3q26.33; chr3:179653145-179789401 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056900 Ensembl Gene Model | MGI Sequence Detail 120526 C57BL/6J ±  kb
transcript ENSMUST00000072312 Ensembl | MGI Sequence Detail 7580 Not Applicable  
polypeptide ENSMUSP00000072155 Ensembl | MGI Sequence Detail 858 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139812
References
more
  • Summaries
    All 31
    Diseases 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227354 Yuan L, et al., Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis. Nat Cell Biol. 2015 Sep;17(9):1169-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory