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Frmd4a Gene Detail
Summary
  • Symbol
    Frmd4a
  • Name
    FERM domain containing 4A
  • Synonyms
    2700017I06Rik, C230040M21Rik, Gm13190, mKIAA1294
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919850
    NCBI Gene: 209630
  • Alliance
  • Transcription Start Sites
    37 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:4017717-4614043 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 2.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3850 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919850
protein coding gene Chr2:4017650-4614043 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025313
protein coding gene Chr2:1032056-1667083 (+)
A/J MGP_AJ_G0025290
protein coding gene Chr2:991750-1589768 (+)
AKR/J MGP_AKRJ_G0025258
protein coding gene Chr2:1007950-1622734 (+)
BALB/cJ MGP_BALBcJ_G0025286
protein coding gene Chr2:958346-1563624 (+)
C3H/HeJ MGP_C3HHeJ_G0025046
protein coding gene Chr2:993791-1611744 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025728
protein coding gene Chr2:1033211-1679593 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023142
protein coding gene Chr2:863718-1448287 (+)
CAST/EiJ MGP_CASTEiJ_G0024509
protein coding gene Chr2:989612-1612510 (+)
CBA/J MGP_CBAJ_G0025025
protein coding gene Chr2:1082374-1754332 (+)
DBA/2J MGP_DBA2J_G0025157
protein coding gene Chr2:959686-1561814 (+)
FVB/NJ MGP_FVBNJ_G0025119
protein coding gene Chr2:957980-1552952 (+)
LP/J MGP_LPJ_G0025243
protein coding gene Chr2:1023042-1643956 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025151
protein coding gene Chr2:1037012-1666152 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025786
protein coding gene Chr2:1000575-1620438 (+)
PWK/PhJ MGP_PWKPhJ_G0024259
protein coding gene Chr2:924858-1532779 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024060
protein coding gene Chr2:996861-1634093 (+)
WSB/EiJ MGP_WSBEiJ_G0024579
protein coding gene Chr2:1006307-1632877 (+)



Homology
more
  • Human Ortholog
    FRMD4A, FERM domain containing 4A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FRMD4A, FERM domain containing 4A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA295P9.4, CCAFCA, FRMD4
  • Links
    NCBI Gene ID: 55691
    neXtProt AC: NX_Q9P2Q2
    UniProt: Q9P2Q2

  • Chr Location
    10p13; chr10:13643706-14330952 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026657 Ensembl Gene Model | MGI Sequence Detail 596327 C57BL/6J ±  kb
transcript ENSMUST00000091497 Ensembl | MGI Sequence Detail 6208 Not Applicable  
polypeptide ENSMUSP00000089079 Ensembl | MGI Sequence Detail 1042 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139010, MGI:2443045, MGI:3711984
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202837 Rowton M, et al., Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. Dev Dyn. 2013 Nov;242(11):1332-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory