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Pdia5 Gene Detail
Summary
  • Symbol
    Pdia5
  • Name
    protein disulfide isomerase associated 5
  • Synonyms
    2700053F16Rik, Pdir
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919849
    NCBI Gene: 72599
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:35217682-35311243 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 25.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2323 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919849
 protein coding gene Chr16:35217678-35311289 (-)
129S1/SvImJ ENSMUSG00200027278
 protein coding gene Chr16:32232845-32326386 (-)
A/J ENSMUSG00195010897
 protein coding gene Chr16:31784113-31877656 (-)
AKR/J ENSMUSG00220025484
 protein coding gene Chr16:32069960-32163522 (-)
BALB/cJ ENSMUSG00180012184
 protein coding gene Chr16:32000050-32093602 (-)
C3H/HeJ ENSMUSG00175030878
 protein coding gene Chr16:32135950-32229495 (-)
C57BL/6NJ ENSMUSG00215012312
 protein coding gene Chr16:32024987-32118529 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020702
 protein coding gene Chr16:32443888-32529580 (-)
CAST/EiJ ENSTCUG00005029822
 protein coding gene Chr16:32405078-32492044 (-)
CBA/J ENSMUSG00210026039
 protein coding gene Chr16:32193118-32286644 (-)
DBA/2J ENSMUSG00185023147
 protein coding gene Chr16:32096232-32189778 (-)
FVB/NJ ENSMUSG00205016941
 protein coding gene Chr16:32132270-32225806 (-)
JF1/MsJ ENSUMUG00000016273
 protein coding gene Chr16:32291775-32378007 (-)
LP/J ENSMUSG00230031195
 protein coding gene Chr16:34660872-34846500 (-)
NOD/ShiLtJ ENSMUSG00190022768
 protein coding gene Chr16:32293148-32386682 (-)
NZO/HlLtJ ENSMUSG00225039526
 protein coding gene Chr16:37910648-38004434 (-)
PWK/PhJ ENSLUMG00010028004
 protein coding gene Chr16:32188569-32275407 (-)
SPRET/EiJ ENSMSPG00010015716
 protein coding gene Chr16:32119988-32206717 (-)
WSB/EiJ ENSIUOG00005024832
 protein coding gene Chr16:32257686-32351256 (-)



Homology
more
  • Human Ortholog
    PDIA5, protein disulfide isomerase family A member 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDIA5, protein disulfide isomerase family A member 5
  • Synonyms
    PDIR
  • Links
    NCBI Gene ID: 10954
    UniProt: Q14554

  • Chr Location
    3q21.1; chr3:123067025-123225227 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    645
  • Tissues
    6
  • cDNA Data
    60
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022844 Ensembl Gene Model | MGI Sequence Detail 93562 C57BL/6J ±  kb
transcript ENSMUST00000023550 Ensembl | MGI Sequence Detail 1809 Not Applicable  
polypeptide ENSMUSP00000023550 Ensembl | MGI Sequence Detail 517 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 60
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146538
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:113814 Hayano T, et al., Molecular cloning of the cDNA encoding a novel protein disulfide isomerase-related protein (PDIR). FEBS Lett. 1995 Sep 25;372(2-3):210-4
  • Latest
    J:362983 Chen F, et al., Differential transport pathways of saturated and unsaturated fatty acid esters in male mouse hepatocytes. Nat Commun. 2025 Feb 4;16(1):1344
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory