About   Help   FAQ
Pan3 Gene Detail
Summary
  • Symbol
    Pan3
  • Name
    PAN3 poly(A) specific ribonuclease subunit
  • Synonyms
    2700050F09Rik, A430027N15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919837
    NCBI Gene: 72587
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:147430161-147548502 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 86.93 cM, cytoband G2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    311 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919837
protein coding gene Chr5:147430006-147548502 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030390
protein coding gene Chr5:153095618-153229685 (+)
A/J MGP_AJ_G0030363
protein coding gene Chr5:146600747-146721377 (+)
AKR/J MGP_AKRJ_G0030290
protein coding gene Chr5:151104028-151235163 (+)
BALB/cJ MGP_BALBcJ_G0030372
protein coding gene Chr5:147813014-147934065 (+)
C3H/HeJ MGP_C3HHeJ_G0030086
protein coding gene Chr5:152075468-152200957 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030827
protein coding gene Chr5:158685761-158824361 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028040
protein coding gene Chr5:141012591-141133829 (+)
CAST/EiJ MGP_CASTEiJ_G0029488
protein coding gene Chr5:151646381-151775136 (+)
CBA/J MGP_CBAJ_G0030064
protein coding gene Chr5:165327247-165476844 (+)
DBA/2J MGP_DBA2J_G0030208
protein coding gene Chr5:146281526-146403432 (+)
FVB/NJ MGP_FVBNJ_G0030162
protein coding gene Chr5:145486368-145606267 (+)
LP/J MGP_LPJ_G0030295
protein coding gene Chr5:153791741-153915904 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030198
protein coding gene Chr5:167582195-167709743 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030857
protein coding gene Chr5:151016956-151140519 (+)
PWK/PhJ MGP_PWKPhJ_G0029202
protein coding gene Chr5:145381459-145503054 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029038
protein coding gene Chr5:148341375-148471380 (+)
WSB/EiJ MGP_WSBEiJ_G0029565
protein coding gene Chr5:151824617-151953952 (+)



Homology
more
  • Human Ortholog
    PAN3, poly(A) specific ribonuclease subunit PAN3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PAN3, poly(A) specific ribonuclease subunit PAN3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 255967
    neXtProt AC: NX_Q58A45
    UniProt: Q58A45

  • Chr Location
    13q12.2; chr13:28138079-28295338 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6372
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PAN3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029647 Ensembl Gene Model | MGI Sequence Detail 118342 C57BL/6J ±  kb
transcript ENSMUST00000176600 Ensembl | MGI Sequence Detail 5541 Not Applicable  
polypeptide ENSMUSP00000135367 Ensembl | MGI Sequence Detail 887 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR030844 PAN2-PAN3 deadenylation complex subunit PAN3
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR000571 Zinc finger, CCCH-type
    IPR036855 Zinc finger, CCCH-type superfamily
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 7
Other
Accession IDs
less
MGI:2141025, MGI:2443274
References
more
  • Summaries
    All 31
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory