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Zup1 Gene Detail
Summary
  • Symbol
    Zup1
  • Name
    zinc finger containing ubiquitin peptidase 1
  • Synonyms
    2700019D07Rik, Zufsp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919830
    NCBI Gene: 72580
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:33919142-33951269 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 18.85 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919830
protein coding gene Chr10:33919142-33951345 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017130
protein coding gene Chr10:32254706-32280122 (-)
A/J MGP_AJ_G0017107
protein coding gene Chr10:31400976-31434256 (-)
AKR/J MGP_AKRJ_G0017067
protein coding gene Chr10:31766939-31798851 (-)
BALB/cJ MGP_BALBcJ_G0017070
protein coding gene Chr10:31339927-31375028 (-)
C3H/HeJ MGP_C3HHeJ_G0016890
protein coding gene Chr10:32064025-32097139 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017528
protein coding gene Chr10:33177084-33202226 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015225
protein coding gene Chr10:29758123-29783211 (-)
CAST/EiJ MGP_CASTEiJ_G0016469
protein coding gene Chr10:32186278-32218474 (-)
CBA/J MGP_CBAJ_G0016864
protein coding gene Chr10:34777695-34809495 (-)
DBA/2J MGP_DBA2J_G0016969
protein coding gene Chr10:30984811-31017325 (-)
FVB/NJ MGP_FVBNJ_G0016964
protein coding gene Chr10:30490409-30525073 (-)
LP/J MGP_LPJ_G0017046
protein coding gene Chr10:32242508-32267366 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016994
protein coding gene Chr10:35247954-35295230 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017564
protein coding gene Chr10:31720768-31745037 (-)
PWK/PhJ MGP_PWKPhJ_G0016251
protein coding gene Chr10:30756383-30781007 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016034
protein coding gene Chr10:31604145-31627643 (-)
WSB/EiJ MGP_WSBEiJ_G0016532
protein coding gene Chr10:31928398-31952614 (-)



Homology
more
  • Human Ortholog
    ZUP1, zinc finger containing ubiquitin peptidase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZUP1, zinc finger containing ubiquitin peptidase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf113, DUB, ZUFSP
  • Links
    NCBI Gene ID: 221302
    neXtProt AC: NX_Q96AP4
    UniProt: Q96AP4

  • Chr Location
    6q22.1; chr6:116635618-116668810 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12472
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZUP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039531 Ensembl Gene Model | MGI Sequence Detail 32128 C57BL/6J ±  kb
transcript ENSMUST00000218055 Ensembl | MGI Sequence Detail 2180 Not Applicable  
polypeptide ENSMUSP00000151811 Ensembl | MGI Sequence Detail 577 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 50
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory