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Cdca2 Gene Detail
Summary
  • Symbol
    Cdca2
  • Name
    cell division cycle associated 2
  • Synonyms
    2610311M19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919787
    NCBI Gene: 108912
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:67913780-67953290 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 34.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919787
 protein coding gene Chr14:67910629-67953290 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021504
 protein coding gene Chr14:62419140-62460883 (-)
A/J MGP_AJ_G0021463
 protein coding gene Chr14:60918833-60959067 (-)
AKR/J MGP_AKRJ_G0021439
 protein coding gene Chr14:62999503-63039900 (-)
BALB/cJ MGP_BALBcJ_G0021469
 protein coding gene Chr14:60914042-60953936 (-)
C3H/HeJ MGP_C3HHeJ_G0021246
 protein coding gene Chr14:62727817-62767353 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021908
 protein coding gene Chr14:65256140-65298309 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019448
 protein coding gene Chr14:58819125-58867108 (-)
CAST/EiJ MGP_CASTEiJ_G0020763
 protein coding gene Chr14:59225328-59265698 (-)
CBA/J MGP_CBAJ_G0021213
 protein coding gene Chr14:67265285-67306995 (-)
DBA/2J MGP_DBA2J_G0021336
 protein coding gene Chr14:60552667-60592193 (-)
FVB/NJ MGP_FVBNJ_G0021315
 protein coding gene Chr14:59957384-59996917 (-)
LP/J MGP_LPJ_G0021411
 protein coding gene Chr14:63475021-63514519 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021344
 protein coding gene Chr14:66243312-66282865 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021931
 protein coding gene Chr14:62230403-62270663 (-)
PWK/PhJ MGP_PWKPhJ_G0020507
 protein coding gene Chr14:57316988-57357412 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020340
 protein coding gene Chr14:58172502-58213572 (-)
WSB/EiJ MGP_WSBEiJ_G0020816
 protein coding gene Chr14:62557624-62599522 (-)



Homology
more
  • Human Ortholog
    CDCA2, cell division cycle associated 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDCA2, cell division cycle associated 2
  • Synonyms
    PPP1R81, Repo-Man
  • Links
    NCBI Gene ID: 157313
    UniProt: Q69YH5

  • Chr Location
    8p21.2; chr8:25458931-25507917 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    23
  • cDNA Data
    16
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048922 Ensembl Gene Model | MGI Sequence Detail 39511 C57BL/6J ±  kb
transcript ENSMUST00000163100 Ensembl | MGI Sequence Detail 3841 Not Applicable  
polypeptide ENSMUSP00000127571 Ensembl | MGI Sequence Detail 982 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005220 cell division cycle-associated protein 2
    (term hierarchy)
  • InterPro Domains
    IPR029334 Protein phosphatase 1 binding domain
  • GlyGen
    Q14B71 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 8
Other
Accession IDs
less
MGI:2145675
References
more
  • Summaries
    All 44
    Developmental Gene Expression 8
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:352715 Kang HS, et al., GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression. Cell Mol Life Sci. 2024 Jan 28;81(1):65
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory