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Aldh1b1
Gene Detail
 Symbol
Name
ID
Aldh1b1
aldehyde dehydrogenase 1 family, member B1
MGI:1919785
Synonyms 2700007F14Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
24.35 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:45799022-45804604 bp, + strand
From VEGA annotation of GRCm38

  5583 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115470  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
Gene Tree: Aldh1b1

Human
homologs
Human Homolog ALDH1B1, aldehyde dehydrogenase 1 family, member B1
NCBI Gene ID 219
neXtProt AC  NX_P30837
Human Synonyms  ALDH5, ALDHX
Human Chr (Location)  9p11.1; chr9:38392664-38398665 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Aldh1b1 interacts with 98 markers (Mir26a-1, Mir26a-2, Mir26b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process metabolic process, oxidation-reduction process
Component intracellular membrane-bounded organelle, mitochondrion, ...
Function aldehyde dehydrogenase (NAD) activity, oxidoreductase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (111)    Tissues (97)    Images (13)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 111
cDNA source data(74)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(76) cDNA(74) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006730 (Evidence)
Ensembl Gene ModelENSMUSG00000035561 (Evidence)
Entrez Gene72535 (Evidence)
UniGene331583
DFCITC1574401
DoTSDT.532400
NIA Mouse Gene IndexU004275
EC1.2.1.3
Consensus CDS ProjectCCDS18139.1
International Mouse Knockout Project StatusAldh1b1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006730 VEGA Gene Model | MGI Sequence Detail 5583 C57BL/6J ±  kb
transcript OTTMUST00000015490 VEGA | MGI Sequence Detail 2298 Not Applicable 
polypeptide OTTMUSP00000007139 VEGA | MGI Sequence Detail 519 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016160 Aldehyde dehydrogenase, conserved site
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR016162 Aldehyde dehydrogenase, N-terminal
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003923 aldehyde dehydrogenase X, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:192460 Ioannou M, et al., ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Dev Biol. 2013 Feb 1;374(1):153-63
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory