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Pip4p2 Gene Detail
Summary
  • Symbol
    Pip4p2
  • Name
    phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
  • Synonyms
    2610319K07Rik, Tmem55a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919769
    NCBI Gene: 72519
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:14864076-14915176 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 6.41 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919769
protein coding gene Chr4:14864076-14915501 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028069
protein coding gene Chr4:11677892-11731863 (+)
A/J MGP_AJ_G0028027
protein coding gene Chr4:11417566-11459013 (+)
AKR/J MGP_AKRJ_G0027992
protein coding gene Chr4:11586237-11642262 (+)
BALB/cJ MGP_BALBcJ_G0028038
protein coding gene Chr4:11318297-11373628 (+)
C3H/HeJ MGP_C3HHeJ_G0027768
protein coding gene Chr4:11743050-11799102 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028481
protein coding gene Chr4:12184301-12235253 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025823
protein coding gene Chr4:10660527-10713518 (+)
CAST/EiJ MGP_CASTEiJ_G0027223
protein coding gene Chr4:11542564-11596780 (+)
CBA/J MGP_CBAJ_G0027741
protein coding gene Chr4:12445369-12499320 (+)
DBA/2J MGP_DBA2J_G0027884
protein coding gene Chr4:11271936-11323169 (+)
FVB/NJ MGP_FVBNJ_G0027850
protein coding gene Chr4:11050758-11101361 (+)
LP/J MGP_LPJ_G0027993
protein coding gene Chr4:11792330-11845189 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027883
protein coding gene Chr4:12811325-12866898 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028540
protein coding gene Chr4:11594832-11648698 (+)
PWK/PhJ MGP_PWKPhJ_G0026943
protein coding gene Chr4:11220214-11268169 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026772
protein coding gene Chr4:11472866-11526407 (+)
WSB/EiJ MGP_WSBEiJ_G0027300
protein coding gene Chr4:11620317-11676108 (+)



Homology
more
  • Human Ortholog
    PIP4P2, phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIP4P2, phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
  • Synonyms
    TMEM55A
  • Links
    NCBI Gene ID: 55529
    neXtProt AC: NX_Q8N4L2
    UniProt: Q8N4L2

  • Chr Location
    8q21.3; chr8:90993802-91040872 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028221 Ensembl Gene Model | MGI Sequence Detail 51101 C57BL/6J ±  kb
transcript ENSMUST00000029875 Ensembl | MGI Sequence Detail 2339 Not Applicable  
polypeptide ENSMUSP00000029875 Ensembl | MGI Sequence Detail 257 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 84
    cDNA 84

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140227, MGI:2140507
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:283186 Morioka S, et al., TMEM55a localizes to macrophage phagosomes to downregulate phagocytosis. J Cell Sci. 2018 Mar 6;131(5):jcs213272

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory