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Dzip1l Gene Detail
Summary
  • Symbol
    Dzip1l
  • Name
    DAZ interacting protein 1-like
  • Synonyms
    2610524A10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919757
    NCBI Gene: 72507
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:99629496-99669256 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 51.93 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919757
protein coding gene Chr9:99629496-99670075 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035173
protein coding gene Chr9:101007794-101052108 (+)
A/J MGP_AJ_G0035154
protein coding gene Chr9:97446279-97486723 (+)
AKR/J MGP_AKRJ_G0035086
protein coding gene Chr9:99813315-99855196 (+)
BALB/cJ MGP_BALBcJ_G0035147
protein coding gene Chr9:97133324-97177197 (+)
C3H/HeJ MGP_C3HHeJ_G0034857
protein coding gene Chr9:100235319-100277437 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035667
protein coding gene Chr9:103899745-103945841 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032566
protein coding gene Chr9:95167165-95206954 (+)
CAST/EiJ MGP_CASTEiJ_G0034168
protein coding gene Chr9:100039951-100083952 (+)
CBA/J MGP_CBAJ_G0034825
protein coding gene Chr9:107457153-107506352 (+)
DBA/2J MGP_DBA2J_G0034987
protein coding gene Chr9:96956462-96996770 (+)
FVB/NJ MGP_FVBNJ_G0034935
protein coding gene Chr9:95773414-95813274 (+)
LP/J MGP_LPJ_G0035063
protein coding gene Chr9:101255758-101301276 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034974
protein coding gene Chr9:109372305-109416912 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035689
protein coding gene Chr9:100066487-100108975 (+)
PWK/PhJ MGP_PWKPhJ_G0033875
protein coding gene Chr9:97170560-97211802 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033710
protein coding gene Chr9:100122493-100174114 (+)
WSB/EiJ MGP_WSBEiJ_G0034288
protein coding gene Chr9:99949394-99992773 (+)



Homology
more
  • Human Ortholog
    DZIP1L, DAZ interacting zinc finger protein 1 like
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DZIP1L, DAZ interacting zinc finger protein 1 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DZIP2, PKD5
  • Links
    NCBI Gene ID: 199221
    neXtProt AC: NX_Q8IYY4
    UniProt: Q8IYY4

  • Chr Location
    3q22.3; chr3:138061985-138115862 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Dzip1l mouse models; 1 with human DZIP1L associations

Human Disease Mouse Models
      
IDs
View 2 models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation exhibit early onset, progressive cystic kidney disease, polydactyly, facial clefting, eye defects, and prenatal lethality. Craniofacial defects and lethality are ameliorated in mice with an outbred genetic background.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037784 Ensembl Gene Model | MGI Sequence Detail 39761 C57BL/6J ±  kb
    transcript ENSMUST00000078367 Ensembl | MGI Sequence Detail 3981 Not Applicable  
    polypeptide ENSMUSP00000077475 Ensembl | MGI Sequence Detail 774 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 28

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143112
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 5
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:260445 Wang C, et al., Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse. Development. 2018 Mar 15;145(6)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory