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Hsdl2 Gene Detail
Summary
  • Symbol
    Hsdl2
  • Name
    hydroxysteroid dehydrogenase like 2
  • Synonyms
    2610207I16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919729
    NCBI Gene: 72479
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:59581563-59618689 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 32.69 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1027 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919729
 protein coding gene Chr4:59581515-59618694 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028337
 protein coding gene Chr4:58491484-58533009 (+)
A/J MGP_AJ_G0028298
 protein coding gene Chr4:56241171-56279940 (+)
AKR/J MGP_AKRJ_G0028247
 protein coding gene Chr4:57814824-57852777 (+)
BALB/cJ MGP_BALBcJ_G0028317
 protein coding gene Chr4:56415747-56453778 (+)
C3H/HeJ MGP_C3HHeJ_G0028038
 protein coding gene Chr4:58351626-58393771 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028758
 protein coding gene Chr4:60526351-60569350 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026064
 protein coding gene Chr4:52972347-53014430 (+)
CAST/EiJ MGP_CASTEiJ_G0027476
 protein coding gene Chr4:58070469-58117684 (+)
CBA/J MGP_CBAJ_G0028003
 protein coding gene Chr4:62587511-62626975 (+)
DBA/2J MGP_DBA2J_G0028153
 protein coding gene Chr4:56141517-56178208 (+)
FVB/NJ MGP_FVBNJ_G0028120
 protein coding gene Chr4:55348067-55385525 (+)
LP/J MGP_LPJ_G0028252
 protein coding gene Chr4:58583931-58622785 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028144
 protein coding gene Chr4:65718473-65755305 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028794
 protein coding gene Chr4:58000940-58038391 (+)
PWK/PhJ MGP_PWKPhJ_G0027201
 protein coding gene Chr4:56179439-56220971 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027029
 protein coding gene Chr4:57327521-57366560 (+)
WSB/EiJ MGP_WSBEiJ_G0027554
 protein coding gene Chr4:57989065-58029225 (+)



Homology
more
  • Human Ortholog
    HSDL2, hydroxysteroid dehydrogenase like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HSDL2, hydroxysteroid dehydrogenase like 2
  • Synonyms
    C9orf99, SDR13C1
  • Links
    NCBI Gene ID: 84263
    UniProt: Q6YN16

  • Chr Location
    9q32; chr9:112380080-112472405 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    107
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028383 Ensembl Gene Model | MGI Sequence Detail 37127 C57BL/6J ±  kb
    transcript ENSMUST00000030078 Ensembl | MGI Sequence Detail 2611 Not Applicable  
    polypeptide ENSMUSP00000030078 Ensembl | MGI Sequence Detail 490 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 108
      cDNA 108

      Microarray probesets 6
    References
    more
    • Summaries
      All 35
      Gene Ontology 8
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:349365 Samson N, et al., HSDL2 links nutritional cues to bile acid and cholesterol homeostasis. Sci Adv. 2024 May 31;10(22):eadk9681
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/24/2026
    MGI 6.24     		The Jackson Laboratory