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Slc16a10
Gene Detail
Symbol

Name
ID
Slc16a10
solute carrier family 16 (monocarboxylic acid transporters), member 10
MGI:1919722
Synonyms
2610103N14Rik, Mct10, PRO0813, TAT1
Feature Type
protein coding gene
Genetic Map
Chromosome 10
21.48 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:40033535-40142254 bp, - strand
From Ensembl annotation of GRCm38

  108720 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75089  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc16a10

Human
homologs
Human Homolog SLC16A10, solute carrier family 16 (aromatic amino acid transporter), member 10
NCBI Gene ID 117247
neXtProt AC  NX_Q8TF71
Human Synonyms  MCT10, PRO0813, TAT1
Human Chr (Location)  6q21-q22; chr6:111087525-111223405 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Chemically induced (ENU)(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced null allele exhibit altered amino acid homeostasis.
 
Interactions
Slc16a10 interacts with 348 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process ion transmembrane transport, transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function transporter activity
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (87)    Tissues (28)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 82
RT-PCR 5
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(43) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000019838 (Evidence)
Entrez Gene72472 (Evidence)
UniGene186778
DFCITC1585489, TC1589998, TC1733112, TC1663757, TC1705323
DoTSDT.55203459, DT.101206416, DT.99857354, DT.94371011
NIA Mouse Gene IndexU031708
Consensus CDS ProjectCCDS48543.1
International Mouse Knockout Project StatusSlc16a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019838 Ensembl Gene Model | MGI Sequence Detail 108720 C57BL/6J ±  kb
transcript ENSMUST00000092566 Ensembl | MGI Sequence Detail 5394 Not Applicable 
polypeptide ENSMUSP00000090227 Ensembl | MGI Sequence Detail 512 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(11) UniProt(7)
Polymorphisms
SNPs within 2kb(458 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
Protein Ontology PR:000014945 monocarboxylate transporter 10
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201184 Ferrara AM, et al., Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology. 2013 Jul;154(7):2533-41
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory