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Slc16a10 Gene Detail
Summary
  • Symbol
    Slc16a10
  • Name
    solute carrier family 16 (monocarboxylic acid transporters), member 10
  • Synonyms
    2610103N14Rik, Mct10, PRO0813, TAT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919722
    NCBI Gene: 72472
  • Gene Overview
    MyGene.info: SLC16A10
Location & Maps
more
  • Sequence Map
    Chr10:40033535-40142254 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      108720 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 21.48 cM, cytoband B1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SLC16A10, solute carrier family 16 member 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC16A10, solute carrier family 16 member 10
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MCT10, PRO0813, TAT1
  • Links
    NCBI Gene ID: 117247
    neXtProt AC: NX_Q8TF71

  • Chr Location
    6q21; chr6:111087503-111223405 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Slc16a10
  • Incidental Mutations
Mice homozygous for an ENU-induced null allele exhibit altered amino acid homeostasis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019838 Ensembl Gene Model | MGI Sequence Detail 108720 C57BL/6J ±  kb
transcript ENSMUST00000092566 Ensembl | MGI Sequence Detail 5394 Not Applicable  
polypeptide ENSMUSP00000090227 Ensembl | MGI Sequence Detail 512 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    454 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014945 monocarboxylate transporter 10
  • InterPro Domains
    IPR011701 Major facilitator superfamily
    IPR020846 Major facilitator superfamily domain
    IPR030762 Monocarboxylate transporter 10
Molecular
Reagents
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  • All nucleic 46
    cDNA 43
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227341 Elso CM, et al., Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes. G3 (Bethesda). 2015;5(12):2903-11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory