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Rab38
Gene Detail
 Symbol
Name
ID
Rab38
RAB38, member RAS oncogene family
MGI:1919683
Synonyms 2310011F14Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
49.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:88430273-88491466 bp, + strand
From VEGA annotation of GRCm38

  61194 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21353  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab38

Human
homologs
Human Homolog RAB38, RAB38, member RAS oncogene family
NCBI Gene ID 23682
neXtProt AC  NX_P57729
Human Synonyms  NY-MEL-1, rrGTPbp
Human Chr (Location)  11q14; chr11:88113247-88175467 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Chemically induced (ENU)(1) Endonuclease-mediated(5) Gene trapped(1) Spontaneous(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a spontaneous mutation display oculocutaneous albinism, abnormal lung alveolar structure and aberrant pulmonary surfactant homeostasis.
 
Phenotype Images(2)
Interactions
Rab38 interacts with 127 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process endosome to melanosome transport, melanosome organization, ...
Component cytoplasm, cytoplasmic vesicle, ...
Function AP-1 adaptor complex binding, AP-3 adaptor complex binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (132)    Tissues (18)    Images (46)
Theiler Stages: 17, 19, 20, 23
Assay TypeResults
RNA in situ 132
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025016 (Evidence)
Ensembl Gene ModelENSMUSG00000030559 (Evidence)
Entrez Gene72433 (Evidence)
UniGene276669
DFCITC1580168
DoTSDT.40134532, DT.94180483
NIA Mouse Gene IndexU008351
Consensus CDS ProjectCCDS21439.1
International Mouse Knockout Project StatusRab38
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025016 VEGA Gene Model | MGI Sequence Detail 61194 C57BL/6J ±  kb
transcript OTTMUST00000061576 VEGA | MGI Sequence Detail 1471 Not Applicable 
polypeptide OTTMUSP00000030222 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(304 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013614 ras-related protein Rab-38
References (Earliest) J:13967 MacPike A, et al., New coat color mutations, Dbr and cht. Mouse News Lett. 1984;70:86
(Latest) J:205086 Wefers B, et al., Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3782-7
All references(46)
Other
accession IDs
MGD-MRK-1982, MGI:2142161, MGI:88400

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory