Rab38
Gene Detail

Symbol Name ID

Rab38 RAB38, member of RAS oncogene family MGI:1919683

Synonyms

2310011F14Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 7

49.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr7:88430273-88491466 bp, + strand From VEGA annotation of GRCm38   61194 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:21353  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab38

Human homologs

Human Homolog		RAB38, RAB38, member RAS oncogene family
NCBI Gene ID		23682
neXtProt AC		NX_P57729
Human Synonyms		NY-MEL-1, rrGTPbp
Human Chr (Location)		11q14; chr11:87846415-87908635 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(1) Spontaneous(1)
 

Mice homozygous for a spontaneous mutation display oculocutaneous albinism, abnormal lung alveolar structure and aberrant pulmonary surfactant homeostasis.

 
Phenotype Images(2)

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	organelle organization, phagosome acidification, ...
Component	cytoplasm, cytosol, ...
Function	GTP binding, nucleotide binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (132)    Tissues (18)    Images (46)
Theiler Stages: 17, 19, 20, 23

Assay Type	Results
RNA in situ	132

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(12)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000025016 (Evidence)
Ensembl Gene Model	ENSMUSG00000030559 (Evidence)
Entrez Gene	72433 (Evidence)
UniGene	276669
DFCI	TC1580168
DoTS	DT.40134532, DT.94180483
NIA Mouse Gene Index	U008351
Consensus CDS Project	CCDS21439.1
International Mouse Knockout Project Status	Rab38

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025016	VEGA Gene Model | MGI Sequence Detail	61194	C57BL/6J
transcript	OTTMUST00000061576	VEGA | MGI Sequence Detail	1471	Not Applicable
polypeptide	OTTMUSP00000030222	VEGA | MGI Sequence Detail	211	Not Applicable

All sequences(33) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(261 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013614	ras-related protein Rab-38

References

(Earliest) J:13967 MacPike A, et al., New coat color mutations, Dbr and cht. Mouse News Lett. 1984;70:86
(Latest) J:185512 Meyer M, et al., Modeling disease mutations by gene targeting in one-cell mouse embryos. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9354-9
All references(44)

Other accession IDs

MGD-MRK-1982, MGI:2142161, MGI:88400