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B3gnt1
Gene Detail
 Symbol
Name
ID
B3gnt1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
MGI:1919680
Synonyms 1500032M01Rik, B3gnt6, BETA3GNT1, iGNT
Feature Type protein coding gene
Genetic Map
Chromosome 19
4.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:5038826-5041134 bp, + strand
From NCBI annotation of GRCm38

  2309 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38239  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: B3gnt1

Human
homologs
Human Homolog B3GNT1, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
NCBI Gene ID 11041
neXtProt AC  NX_O43505
Human Synonyms  B3GN-T1, B3GNT6, BETA3GNTI, iGAT, iGNT, MDDGA13
Human Chr (Location)  11q13.2; chr11:66345372-66347690 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human B3GNT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele display altered lymphocyte rolling and abnormal lymph node B and T cell numbers. Mice homozygous for a hypomorphic allele exhibit mild muscular dystrophy, abnormal axon guidance and fasciculation and abnormal dorsal funiculus.
 
Interactions
B3gnt1 interacts with 168 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process axon guidance, poly-N-acetyllactosamine biosynthetic process, ...
Component extracellular vesicular exosome, Golgi apparatus, ...
Function N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (164)    Tissues (104)    Images (26)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 164
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000047379 (Evidence)
Entrez Gene108902 (Evidence)
DFCITC1577737, TC1593580
EC2.4.1.149
Consensus CDS ProjectCCDS29446.1
International Mouse Knockout Project StatusB3gnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 108902 NCBI Gene Model | MGI Sequence Detail 2309 C57BL/6J ±  kb
transcript NM_175383 RefSeq | MGI Sequence Detail 2035 C57BL/6 
polypeptide Q8BWP8 UniProt | EBI | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026603 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
Protein Ontology PR:000004591 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:194150 Wright KM, et al., Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012 Dec 6;76(5):931-44
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory