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Sgol1
Gene Detail
Symbol

Name
ID
Sgol1
shugoshin-like 1 (S. pombe)
MGI:1919665
Synonyms
3300001M08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
27.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:53674786-53689333 bp, - strand
From VEGA annotation of GRCm38

  14548 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23642  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

HCOP human homology predictions: SGOL1
Gene Tree: Sgol1

Human
homologs
SGOL1, shugoshin-like 1 (S. pombe)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 151648
neXtProt AC: NX_Q5FBB7

Human Synonyms: CAID, NY-BR-85, SGO, Sgo1

Human Chr (Location): 3p24.3; chr3:20159046-20188131 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SGOL1

Mutations,
alleles, and
phenotypes
All mutations/alleles(41) : Gene trapped(39) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Sgol1 interacts with 257 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process attachment of spindle microtubules to kinetochore, cell cycle, ...
Component centrosome, chromosome, ...
Function kinase binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (94)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
cDNA source data(72)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sgol1 ; ZFIN sgol1    NEW 
Molecular
reagents
All nucleic(73) Genomic(1) cDNA(72)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000024480 (Evidence)
Ensembl Gene Model ENSMUSG00000023940 (Evidence)
Entrez Gene 72415 (Evidence)
UniGene 153202
DFCI TC1578833, TC1602335, TC1705315, TC1764287
DoTS DT.101379531, DT.101713582, DT.486356
NIA Mouse Gene Index U037920
Consensus CDS Project CCDS28881.1
International Mouse Phenotyping Consortium Status Sgol1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024480 VEGA Gene Model | MGI Sequence Detail 14548 C57BL/6J ±  kb
transcript OTTMUST00000060054 VEGA | MGI Sequence Detail 3628 Not Applicable 
polypeptide OTTMUSP00000029273 VEGA | MGI Sequence Detail 517 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(216 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011515 Shugoshin, C-terminal
InterPro IPR011516 Shugoshin, N-terminal coiled-coil domain
Protein Ontology PR:000014798 shugoshin-like 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:220235 Yamada HY, et al., Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. Carcinogenesis. 2015 Apr;36(4):429-40
All references(40)
Other
accession IDs
MGI:2147138

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory