About   Help   FAQ
Sgol1
Gene Detail
 Symbol
Name
ID
Sgol1
shugoshin-like 1 (S. pombe)
MGI:1919665
Synonyms 3300001M08Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
27.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:53674786-53689333 bp, - strand
From VEGA annotation of GRCm38

  14548 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23642  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

Gene Tree: Sgol1

Human
homologs
Human Homolog SGOL1, shugoshin-like 1 (S. pombe)
NCBI Gene ID 151648
neXtProt AC  NX_Q5FBB7
Human Synonyms  NY-BR-85, SGO, Sgo1
Human Chr (Location)  3p24.3; chr3:20160593-20186232 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(41) : Gene trapped(39) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sgol1 interacts with 258 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process attachment of spindle microtubules to kinetochore, cell cycle, ...
Component centrosome, chromosome, ...
Function kinase binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (94)    Images (7)
Theiler Stages: 22
Assay TypeResults
RNA in situ 95
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(73) Genomic(1) cDNA(72)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000024480 (Evidence)
Ensembl Gene ModelENSMUSG00000023940 (Evidence)
Entrez Gene72415 (Evidence)
UniGene153202
DFCITC1578833, TC1602335, TC1705315, TC1764287
DoTSDT.101379531, DT.101713582, DT.486356
NIA Mouse Gene IndexU037920
Consensus CDS ProjectCCDS28881.1
International Mouse Knockout Project StatusSgol1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024480 VEGA Gene Model | MGI Sequence Detail 14548 C57BL/6J ±  kb
transcript OTTMUST00000060054 VEGA | MGI Sequence Detail 3628 Not Applicable 
polypeptide OTTMUSP00000029273 VEGA | MGI Sequence Detail 517 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(216 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011515 Shugoshin, C-terminal
InterPro IPR011516 Shugoshin, N-terminal
Protein Ontology PR:000014798 shugoshin-like 1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:204809 Yamada HY, et al., Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle. 2012 Feb 1;11(3):479-88
All references(39)
Other
accession IDs
MGI:2147138

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory