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Wdr44 Gene Detail
Summary
  • Symbol
    Wdr44
  • Name
    WD repeat domain 44
  • Synonyms
    2610034K17Rik, DKFZp686L20145, RAB11BP, RPH11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919654
    NCBI Gene: 72404
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:23559290-23672264 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 17.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1890 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919654
 protein coding gene ChrX:23559231-23672265 (+)
129S1/SvImJ ENSMUSG00200015452
 protein coding gene ChrX:18340012-18452986 (+)
A/J ENSMUSG00195007379
 protein coding gene ChrX:18334718-18447706 (+)
AKR/J ENSMUSG00220017829
 protein coding gene ChrX:17819635-17932603 (+)
BALB/cJ ENSMUSG00180021402
 protein coding gene ChrX:18252862-18365840 (+)
C3H/HeJ ENSMUSG00175029098
 protein coding gene ChrX:18317313-18430292 (+)
C57BL/6NJ ENSMUSG00215014047
 protein coding gene ChrX:18904751-19017732 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032982
 protein coding gene ChrX:16841360-16953501 (+)
CAST/EiJ ENSTCUG00005026594
 protein coding gene ChrX:18233857-18346855 (+)
CBA/J ENSMUSG00210020417
 protein coding gene ChrX:18349559-18462537 (+)
DBA/2J ENSMUSG00185030292
 protein coding gene ChrX:24950405-25063390 (+)
FVB/NJ ENSMUSG00205019651
 protein coding gene ChrX:17913859-18026837 (+)
JF1/MsJ ENSUMUG00000023833
 protein coding gene ChrX:38760017-38873875 (+)
LP/J ENSMUSG00230006238
 protein coding gene ChrX:29526361-29639333 (+)
NOD/ShiLtJ ENSMUSG00190024056
 protein coding gene ChrX:18331352-18444338 (+)
NZO/HlLtJ ENSMUSG00225041111
 protein coding gene ChrX:34759360-34872348 (+)
PWK/PhJ ENSLUMG00010016112
 protein coding gene ChrX:18205261-18319169 (+)
SPRET/EiJ ENSMSPG00010010102
 protein coding gene ChrX:19603165-19728677 (+)
WSB/EiJ ENSIUOG00005030113
 protein coding gene ChrX:14938804-15051809 (+)



Homology
more
  • Human Ortholog
    WDR44, WD repeat domain 44
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR44, WD repeat domain 44
  • Synonyms
    RAB11BP, RPH11, SYM-4
  • Links
    NCBI Gene ID: 54521
    UniProt: Q5JSH3

  • Chr Location
    Xq24; chrX:118345968-118450285 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 images
    5 phenotype references
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    1
  • cDNA Data
    30
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036769 Ensembl Gene Model | MGI Sequence Detail 112975 C57BL/6J ±  kb
transcript ENSMUST00000035766 Ensembl | MGI Sequence Detail 4167 Not Applicable  
polypeptide ENSMUSP00000044616 Ensembl | MGI Sequence Detail 915 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 30

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:382293 Baron Y, et al., VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase. BMC Biol. 2014 May 29;12:39
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory