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Borcs8 Gene Detail
Summary
  • Symbol
    Borcs8
  • Name
    BLOC-1 related complex subunit 8
  • Synonyms
    2310045N01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919618
    NCBI Gene: 72368
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:70592149-70599969 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919618
 protein coding gene Chr8:70592149-70601285 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033692
 protein coding gene Chr8:70388172-70420687 (+)
A/J MGP_AJ_G0033675
 protein coding gene Chr8:67526273-67555071 (+)
AKR/J MGP_AKRJ_G0033600
 protein coding gene Chr8:69447141-69475978 (+)
BALB/cJ MGP_BALBcJ_G0033671
 protein coding gene Chr8:67755943-67783854 (+)
C3H/HeJ MGP_C3HHeJ_G0033381
 protein coding gene Chr8:70091695-70125108 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034188
 protein coding gene Chr8:73046325-73088223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031132
 protein coding gene Chr8:62345928-62375060 (+)
CAST/EiJ MGP_CASTEiJ_G0032706
 protein coding gene Chr8:69578777-69604869 (+)
CBA/J MGP_CBAJ_G0033359
 protein coding gene Chr8:75694099-75724968 (+)
DBA/2J MGP_DBA2J_G0033513
 protein coding gene Chr8:67252929-67282886 (+)
FVB/NJ MGP_FVBNJ_G0033454
 protein coding gene Chr8:66354390-66384638 (+)
LP/J MGP_LPJ_G0033600
 protein coding gene Chr8:70427880-70455381 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033498
 protein coding gene Chr8:78350168-78360459 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034206
 protein coding gene Chr8:69627046-69659827 (+)
PWK/PhJ MGP_PWKPhJ_G0032414
 protein coding gene Chr8:66538518-66569021 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032250
 protein coding gene Chr8:68601855-68631056 (+)
WSB/EiJ MGP_WSBEiJ_G0032821
 protein coding gene Chr8:69988595-70021602 (+)



Homology
more
  • Human Ortholog
    BORCS8, BLOC-1 related complex subunit 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BORCS8, BLOC-1 related complex subunit 8
  • Synonyms
    MEF2BNB
  • Links
    NCBI Gene ID: 729991
    neXtProt AC: NX_Q96FH0
    UniProt: Q96FH0

  • Chr Location
    19p13.11; chr19:19176903-19192591 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    23
  • cDNA Data
    64
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002345 Ensembl Gene Model | MGI Sequence Detail 7821 C57BL/6J ±  kb
transcript ENSMUST00000002418 Ensembl | MGI Sequence Detail 810 Not Applicable  
polypeptide ENSMUSP00000002418 Ensembl | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:28211 Hidaka K, et al., The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells. Biochem Biophys Res Commun. 1995 Aug 15;213(2):555-60
  • Latest
    J:321899 Park H, et al., Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice. Neurosci Res. 2019 Oct;147:58-63
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory