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Zfyve27
Gene Detail
 Symbol
Name
ID
Zfyve27
zinc finger, FYVE domain containing 27
MGI:1919602
Synonyms 2210011N02Rik, 9530077C24Rik, protrudin
Feature Type protein coding gene
Genetic Map
Chromosome 19
35.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:42163951-42194590 bp, + strand
From VEGA annotation of GRCm38

  30640 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16939  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zfyve27

Human
homologs
Human Homolog ZFYVE27, zinc finger, FYVE domain containing 27
NCBI Gene ID 118813
neXtProt AC  NX_Q5T4F4
Human Synonyms  PROTRUDIN, SPG33
Human Chr (Location)  10q24.2; chr10:97737121-97760907 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ZFYVE27
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Zfyve27 interacts with 328 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process neuron projection development, neurotrophin TRK receptor signaling pathway, ...
Component axon, cell projection, ...
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (92)    Tissues (27)    Images (25)
Theiler Stages: 23
Assay TypeResults
RNA in situ 92
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000035213 (Evidence)
Ensembl Gene ModelENSMUSG00000018820 (Evidence)
Entrez Gene319740 (Evidence)
DFCITC1576723, TC1611792, TC1628016, TC1629272
NIA Mouse Gene IndexU040845
Consensus CDS ProjectCCDS29825.2, CCDS50440.1
International Mouse Knockout Project StatusZfyve27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035213 VEGA Gene Model | MGI Sequence Detail 30640 C57BL/6J ±  kb
transcript OTTMUST00000089700 VEGA | MGI Sequence Detail 5611 Not Applicable 
polypeptide OTTMUSP00000049047 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(139 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR017455 Zinc finger, FYVE-related
InterPro IPR000306 Zinc finger, FYVE-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000030416 protrudin
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2147526, MGI:2147581, MGI:2147597, MGI:2442645

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory