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Zfyve27 Gene Detail
Summary
  • Symbol
    Zfyve27
  • Name
    zinc finger, FYVE domain containing 27
  • Synonyms
    2210011N02Rik, 9530077C24Rik, protrudin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919602
    NCBI Gene: 319740
Location & Maps
more
  • Sequence Map
    Chr19:42163951-42194590 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30640 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    ZFYVE27, zinc finger, FYVE domain containing 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZFYVE27, zinc finger, FYVE domain containing 27
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PROTRUDIN, SPG33
  • Links
    NCBI Gene ID: 118813
    neXtProt AC: NX_Q5T4F4

  • Chr Location
    10q24.2; chr10:97737121-97760907 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ZFYVE27 associations

Human Disease Mouse Models
       Spastic Paraplegia 33, Autosomal Dominant; SPG33   OMIM: 610244
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    4
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035213 VEGA Gene Model | MGI Sequence Detail 30640 C57BL/6J ±  kb
transcript OTTMUST00000089700 VEGA | MGI Sequence Detail 5611 Not Applicable  
polypeptide OTTMUSP00000049047 VEGA | MGI Sequence Detail 415 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    139 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
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  • All nucleic 14
    cDNA 14

    Microarray probesets 7
Other
Accession IDs
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MGI:2147526, MGI:2147581, MGI:2147597, MGI:2442645
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:221584 Quesnel-Vallieres M, et al., Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory