About   Help   FAQ
Zfyve27 Gene Detail
Summary
  • Symbol
    Zfyve27
  • Name
    zinc finger, FYVE domain containing 27
  • Synonyms
    2210011N02Rik, 9530077C24Rik, protrudin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919602
    NCBI Gene: 319740
  • Gene Overview
    MyGene.info: ZFYVE27
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:42170567-42194593 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 35.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919602
protein coding gene Chr19:42163951-42194593 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025142
protein coding gene Chr19:41489216-41522477 (+)
A/J MGP_AJ_G0025119
protein coding gene Chr19:39492074-39523732 (+)
AKR/J MGP_AKRJ_G0025087
protein coding gene Chr19:40782706-40813342 (+)
BALB/cJ MGP_BALBcJ_G0025113
protein coding gene Chr19:39557766-39588401 (+)
C3H/HeJ MGP_C3HHeJ_G0024873
protein coding gene Chr19:40935825-40967456 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025556
protein coding gene Chr19:42551735-42582377 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022970
protein coding gene Chr19:38845515-38880269 (+)
CAST/EiJ MGP_CASTEiJ_G0024338
protein coding gene Chr19:40614917-40649360 (+)
CBA/J MGP_CBAJ_G0024853
protein coding gene Chr19:44633173-44663814 (+)
DBA/2J MGP_DBA2J_G0024985
protein coding gene Chr19:39339240-39369778 (+)
FVB/NJ MGP_FVBNJ_G0024946
protein coding gene Chr19:39114539-39145267 (+)
LP/J MGP_LPJ_G0025071
protein coding gene Chr19:41474806-41505442 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024977
protein coding gene Chr19:44257319-44289361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025614
protein coding gene Chr19:40829777-40864587 (+)
PWK/PhJ MGP_PWKPhJ_G0024087
protein coding gene Chr19:39228791-39262166 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023891
protein coding gene Chr19:39571813-39608474 (+)
WSB/EiJ MGP_WSBEiJ_G0024408
protein coding gene Chr19:40981220-41012911 (+)



Homology
more
  • Human Ortholog
    ZFYVE27, zinc finger FYVE-type containing 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZFYVE27, zinc finger FYVE-type containing 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PROTRUDIN, SPG33
  • Links
    NCBI Gene ID: 118813
    neXtProt AC: NX_Q5T4F4
    UniProt: Q5T4F4

  • Chr Location
    10q24.2; chr10:97737121-97760907 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ZFYVE27 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319740 NCBI Gene Model | MGI Sequence Detail 24027 C57BL/6J ±  kb
transcript NM_177319 RefSeq | MGI Sequence Detail 5636 C57BL/6  
polypeptide Q3TXX3 UniProt | EBI | MGI Sequence Detail 415 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
less
MGI:2147526, MGI:2147581, MGI:2147597, MGI:2442645
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:259138 Oliver JA, et al., A Subpopulation of Label-Retaining Cells of the Kidney Papilla Regenerates Injured Kidney Medullary Tubules. Stem Cell Reports. 2016 May 10;6(5):757-771

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory