Zfyve27
Gene Detail

Symbol Name ID

Zfyve27 zinc finger, FYVE domain containing 27 MGI:1919602

Synonyms

2210011N02Rik, 9530077C24Rik, protrudin

Feature Type

protein coding gene

Genetic Map

Chromosome 19

35.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:42163951-42194590 bp, + strand From VEGA annotation of GRCm38   30640 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:16939  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Zfyve27

Human homologs

Human Homolog		ZFYVE27, zinc finger, FYVE domain containing 27
NCBI Gene ID		118813
neXtProt AC		NX_Q5T4F4
Human Synonyms		PROTRUDIN, RP11-459F3.2, SPG33
Human Chr (Location)		10q24.2; chr10:99496878-99520664 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ZFYVE27

Alleles and phenotypes

All alleles(6) : Targeted(2) Gene trapped(4)

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	neuron projection development, neurotrophin TRK receptor signaling pathway, ...
Component	axon, cell projection, ...
Function	metal ion binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (92)    Tissues (27)    Images (25)
Theiler Stages: 23

Assay Type	Results
RNA in situ	92

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(14)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000035213 (Evidence)
Ensembl Gene Model	ENSMUSG00000018820 (Evidence)
Entrez Gene	319740 (Evidence)
DFCI	TC1576723, TC1611792, TC1628016, TC1629272
NIA Mouse Gene Index	U040845
Consensus CDS Project	CCDS29825.2, CCDS50440.1
International Mouse Knockout Project Status	Zfyve27

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035213	VEGA Gene Model | MGI Sequence Detail	30640	C57BL/6J
transcript	OTTMUST00000089700	VEGA | MGI Sequence Detail	5611	Not Applicable
polypeptide	OTTMUSP00000049047	VEGA | MGI Sequence Detail	415	Not Applicable

All sequences(56) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(122 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011011	Zinc finger, FYVE/PHD-type
InterPro	IPR017455	Zinc finger, FYVE-related
InterPro	IPR000306	Zinc finger, FYVE-type
InterPro	IPR013083	Zinc finger, RING/FYVE/PHD-type
Protein Ontology	PR:000030416	protrudin

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGI:2147526, MGI:2147581, MGI:2147597, MGI:2442645