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Zfyve27
Gene Detail
Symbol

Name
ID
Zfyve27
zinc finger, FYVE domain containing 27
MGI:1919602
Synonyms
2210011N02Rik, 9530077C24Rik, protrudin
Feature Type
protein coding gene
Genetic Map
Chromosome 19
35.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:42163951-42194590 bp, + strand
From VEGA annotation of GRCm38

  30640 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16939  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ZFYVE27
Gene Tree: Zfyve27

Human
homologs
ZFYVE27, zinc finger, FYVE domain containing 27
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 118813
neXtProt AC: NX_Q5T4F4

Human Synonyms: PROTRUDIN, SPG33

Human Chr (Location): 10q24.2; chr10:97737121-97760907 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ZFYVE27

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Zfyve27 interacts with 327 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process neuron projection development, neurotrophin TRK receptor signaling pathway, ...
Component axon, cell projection, ...
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (92)    Tissues (27)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 92
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase zfyve27 ; ZFIN zfyve27    NEW 
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000035213 (Evidence)
Ensembl Gene Model ENSMUSG00000018820 (Evidence)
Entrez Gene 319740 (Evidence)
DFCI TC1576723, TC1628016, TC1611792, TC1629272
NIA Mouse Gene Index U040845
Consensus CDS Project CCDS29825.2, CCDS50440.1
International Mouse Phenotyping Consortium Status Zfyve27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035213 VEGA Gene Model | MGI Sequence Detail 30640 C57BL/6J ±  kb
transcript OTTMUST00000089700 VEGA | MGI Sequence Detail 5611 Not Applicable 
polypeptide OTTMUSP00000049047 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(139 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR017455 Zinc finger, FYVE-related
InterPro IPR000306 Zinc finger, FYVE-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000030416 protrudin
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2147526, MGI:2147581, MGI:2147597, MGI:2442645

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory