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Pcf11 Gene Detail
Summary
  • Symbol
    Pcf11
  • Name
    PCF11 cleavage and polyadenylation factor subunit
  • Synonyms
    2500001H09Rik, 5730417B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919579
    NCBI Gene: 74737
Location & Maps
more
  • Sequence Map
    Chr7:92643543-92669934 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26392 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 51.56 cM, cytoband E2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PCF11, PCF11 cleavage and polyadenylation factor subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PCF11, PCF11 cleavage and polyadenylation factor subunit
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 51585
    neXtProt AC: NX_O94913

  • Chr Location
    11q14.1; chr11:83157095-83185794 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Pcf11
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029291 VEGA Gene Model | MGI Sequence Detail 26392 C57BL/6J ±  kb
transcript OTTMUST00000072585 VEGA | MGI Sequence Detail 5995 Not Applicable  
polypeptide OTTMUSP00000037405 VEGA | MGI Sequence Detail 1553 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    194 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1921987, MGI:2142322
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 27
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory