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Plxdc1 Gene Detail
Summary
  • Symbol
    Plxdc1
  • Name
    plexin domain containing 1
  • Synonyms
    2410003I07Rik, Tem7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919574
    NCBI Gene: 72324
  • Gene Overview
    MyGene.info: PLXDC1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97923238-97986444 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 61.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919574
protein coding gene Chr11:97923237-97986668 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019045
protein coding gene Chr11:100410728-100476037 (-)
A/J MGP_AJ_G0019013
protein coding gene Chr11:96256992-96319290 (-)
AKR/J MGP_AKRJ_G0018983
protein coding gene Chr11:99240689-99306115 (-)
BALB/cJ MGP_BALBcJ_G0018986
protein coding gene Chr11:96754925-96817828 (-)
C3H/HeJ MGP_C3HHeJ_G0018800
protein coding gene Chr11:99367355-99432950 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019439
protein coding gene Chr11:103498644-103566693 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017070
protein coding gene Chr11:93707890-93771784 (-)
CAST/EiJ MGP_CASTEiJ_G0018354
protein coding gene Chr11:100236750-100301238 (-)
CBA/J MGP_CBAJ_G0018771
protein coding gene Chr11:107791406-107861871 (-)
DBA/2J MGP_DBA2J_G0018879
protein coding gene Chr11:95807562-95870124 (-)
FVB/NJ MGP_FVBNJ_G0018868
protein coding gene Chr11:95304077-95370580 (-)
LP/J MGP_LPJ_G0018949
protein coding gene Chr11:100902876-100970964 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018895
protein coding gene Chr11:107609098-107680919 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019479
protein coding gene Chr11:99557533-99625282 (-)
PWK/PhJ MGP_PWKPhJ_G0018126
protein coding gene Chr11:96794187-96859786 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017916
protein coding gene Chr11:99275421-99339648 (-)
WSB/EiJ MGP_WSBEiJ_G0018404
protein coding gene Chr11:99460923-99526855 (-)



Homology
more
  • Human Ortholog
    PLXDC1, plexin domain containing 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PLXDC1, plexin domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TEM3, TEM7
  • Links
    NCBI Gene ID: 57125
    neXtProt AC: NX_Q8IUK5
    UniProt: Q8IUK5

  • Chr Location
    17q12; chr17:39063303-39151649 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017417 Ensembl Gene Model | MGI Sequence Detail 63207 C57BL/6J ±  kb
transcript ENSMUST00000107565 Ensembl | MGI Sequence Detail 2439 Not Applicable  
polypeptide ENSMUSP00000103191 Ensembl | MGI Sequence Detail 507 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144296
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory