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Ccdc74a Gene Detail
Summary
  • Symbol
    Ccdc74a
  • Name
    coiled-coil domain containing 74A
  • Synonyms
    2310015A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919565
    NCBI Gene: 72315
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17464334-17468602 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 10.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919565
protein coding gene Chr16:17464334-17468602 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022588
protein coding gene Chr16:14817150-14821418 (+)
A/J MGP_AJ_G0022549
protein coding gene Chr16:14080617-14084885 (+)
AKR/J MGP_AKRJ_G0022526
protein coding gene Chr16:14625603-14629871 (+)
BALB/cJ MGP_BALBcJ_G0022552
protein coding gene Chr16:14234956-14239224 (+)
C3H/HeJ MGP_C3HHeJ_G0022319
protein coding gene Chr16:14777034-14781302 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023003
protein coding gene Chr16:15046960-15052396 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020523
protein coding gene Chr16:14134270-14138580 (+)
CAST/EiJ MGP_CASTEiJ_G0021847
protein coding gene Chr16:14683262-14687600 (+)
CBA/J MGP_CBAJ_G0022290
protein coding gene Chr16:15719328-15723596 (+)
DBA/2J MGP_DBA2J_G0022420
protein coding gene Chr16:13995028-13999296 (+)
FVB/NJ MGP_FVBNJ_G0022396
protein coding gene Chr16:14035677-14039945 (+)
LP/J MGP_LPJ_G0022487
protein coding gene Chr16:14570541-14574809 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022417
protein coding gene Chr16:15409996-15414264 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023014
protein coding gene Chr16:14573967-14578235 (+)
PWK/PhJ MGP_PWKPhJ_G0021590
protein coding gene Chr16:14251298-14255645 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021418
protein coding gene Chr16:14545510-14549869 (+)
WSB/EiJ MGP_WSBEiJ_G0021894
protein coding gene Chr16:14562000-14566270 (+)



Homology
more
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC74A, coiled-coil domain containing 74A
  • Links
    NCBI Gene ID: 90557
    neXtProt AC: NX_Q96AQ1
    UniProt: Q96AQ1

  • Chr Location
    2q21.1; chr2:131522621-131533666 (+)  GRCh38.p7

  • Human Ortholog
    CCDC74B, coiled-coil domain containing 74B
  • Links
    NCBI Gene ID: 91409
    neXtProt AC: NX_Q96LY2
    UniProt: Q96LY2

  • Chr Location
    2q21.1; chr2:130139283-130145134 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 72315 NCBI Gene Model | MGI Sequence Detail 4269 C57BL/6J ±  kb
transcript NM_001166164 RefSeq | MGI Sequence Detail 1278 C57BL/6  
polypeptide NP_001159636 RefSeq | MGI Sequence Detail 364 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR039496 CCDC92/74, coiled-coil domain
    IPR040370 Coiled-coil domain-containing protein 74A/74B/92
    IPR029422 Coiled coil protein 74, C-terminal
Molecular
Reagents
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  • All nucleic 16
    cDNA 16

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Diseases 1
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:285407 Saito R, et al., Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus. Transl Psychiatry. 2020 Feb 5;10(1):35

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory