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Rusc1 Gene Detail
Summary
  • Symbol
    Rusc1
  • Name
    RUN and SH3 domain containing 1
  • Synonyms
    2210403N08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919546
    NCBI Gene: 72296
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89083981-89093311 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.01 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    23 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919546
 protein coding gene Chr3:89083975-89093363 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027414
 protein coding gene Chr3:89268369-89277699 (-)
A/J MGP_AJ_G0027378
 protein coding gene Chr3:86323616-86332958 (-)
AKR/J MGP_AKRJ_G0027342
 protein coding gene Chr3:88409155-88418497 (-)
BALB/cJ MGP_BALBcJ_G0027387
 protein coding gene Chr3:86292646-86301976 (-)
C3H/HeJ MGP_C3HHeJ_G0027129
 protein coding gene Chr3:88610244-88619586 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027833
 protein coding gene Chr3:92634949-92644279 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025185
 protein coding gene Chr3:81809899-81819423 (-)
CAST/EiJ MGP_CASTEiJ_G0026575
 protein coding gene Chr3:88954293-88963615 (-)
CBA/J MGP_CBAJ_G0027103
 protein coding gene Chr3:95825581-95834927 (-)
DBA/2J MGP_DBA2J_G0027241
 protein coding gene Chr3:85708340-85717670 (-)
FVB/NJ MGP_FVBNJ_G0027209
 protein coding gene Chr3:84036758-84046096 (-)
LP/J MGP_LPJ_G0027350
 protein coding gene Chr3:90351682-90361012 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027229
 protein coding gene Chr3:102046374-102055704 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027892
 protein coding gene Chr3:88161004-88170346 (-)
PWK/PhJ MGP_PWKPhJ_G0026309
 protein coding gene Chr3:85570072-85579514 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026128
 protein coding gene Chr3:87327979-87337300 (-)
WSB/EiJ MGP_WSBEiJ_G0026657
 protein coding gene Chr3:88549847-88559177 (-)



Homology
more
  • Human Ortholog
    RUSC1, RUN and SH3 domain containing 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RUSC1, RUN and SH3 domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NESCA
  • Links
    NCBI Gene ID: 23623
    neXtProt AC: NX_Q9BVN2
    UniProt: Q9BVN2

  • Chr Location
    1q22; chr1:155320849-155331118 (+)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    138
  • Tissues
    17
  • cDNA Data
    60
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041263 Ensembl Gene Model | MGI Sequence Detail 9331 C57BL/6J ±  kb
transcript ENSMUST00000090929 Ensembl | MGI Sequence Detail 3706 Not Applicable  
polypeptide ENSMUSP00000088447 Ensembl | MGI Sequence Detail 1030 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 60

    Microarray probesets 7
Other
Accession IDs
less
MGI:2139558
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:209602 Li CL, et al., SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons. J Neurosci. 2014 Mar 12;34(11):4027-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/13/2019
MGI 6.14 		The Jackson Laboratory