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Malat1 Gene Detail
Summary
  • Symbol
    Malat1
  • Name
    metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
  • Synonyms
    2210401K01Rik, 9430072K23Rik, NEAT2
  • Feature Type
    lincRNA gene
  • IDs
    MGI:1919539
    NCBI Gene: 72289
  • Gene Overview
    MyGene.info: MALAT1
Location & Maps
more
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    MALAT1, metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
  • Human Ortholog
    MALAT1, metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
    Orthology source: HGNC
  • Synonyms
    HCN, LINC00047, mascRNA, NCRNA00047, NEAT2, PRO2853
  • Links
    NCBI Gene ID: 378938
    neXtProt AC: NX_Q9UHZ2

  • Chr Location
    11q13.1; chr11:65497762-65506469 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
  • All Mutations and Alleles
    17
  • Gene trapped
    15
  • Targeted
    2
Mice homozygous for a knock-out allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037798 VEGA Gene Model | MGI Sequence Detail 6983 C57BL/6J ±  kb
transcript OTTMUST00000097547 VEGA | MGI Sequence Detail 6983 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    47 from dbSNP Build 142
Molecular
Reagents
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  • All nucleic 20
    cDNA 17
    Primer pair 1
    Other 2

    Microarray probesets 6
Other
Accession IDs
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MGI:1924542, MGI:2147588
References
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  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227688 Arun G, et al., Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev. 2016 Jan 1;30(1):34-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
09/13/2016
MGI 6.05
The Jackson Laboratory