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Sh2d4a Gene Detail
Summary
  • Symbol
    Sh2d4a
  • Name
    SH2 domain containing 4A
  • Synonyms
    2210402M20Rik, SH2A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919531
    NCBI Gene: 72281
  • Gene Overview
    MyGene.info: SH2D4A
Location & Maps
more
  • Sequence Map
    Chr8:68276567-68347694 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      71128 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 33.76 cM, cytoband C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SH2D4A, SH2 domain containing 4A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SH2D4A, SH2 domain containing 4A
    Orthology source: HomoloGene
  • Synonyms
    PPP1R38, SH2A
  • Links
    NCBI Gene ID: 63898
    neXtProt AC: NX_Q9H788

  • Chr Location
    8p21.2; chr8:19313443-19396218 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Sh2d4a
  • Incidental Mutations
Mice homozygous for a knock-out allele display normal T cell development, homeostasis, proliferation, and function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029939 VEGA Gene Model | MGI Sequence Detail 71128 C57BL/6J ±  kb
transcript OTTMUST00000074276 VEGA | MGI Sequence Detail 2718 Not Applicable  
polypeptide OTTMUSP00000038600 VEGA | MGI Sequence Detail 421 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    706 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029751 SH2 domain-containing protein 4A
  • InterPro Domains
    IPR000980 SH2 domain
Molecular
Reagents
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  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory