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Dnajc24 Gene Detail
Summary
  • Symbol
    Dnajc24
  • Name
    DnaJ heat shock protein family (Hsp40) member C24
  • Synonyms
    1700030A21Rik, 2610027M02Rik, Dph4, MmDjC7, Zcsl3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919522
    NCBI Gene: 99349
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:105966709-106003549 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 55.46 cM, cytoband E3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919522
protein coding gene Chr2:105966708-106003549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026233
protein coding gene Chr2:108147430-108190605 (-)
A/J MGP_AJ_G0026194
protein coding gene Chr2:103640422-103682038 (-)
AKR/J MGP_AKRJ_G0026174
protein coding gene Chr2:106479395-106517324 (-)
BALB/cJ MGP_BALBcJ_G0026203
protein coding gene Chr2:103917121-103954218 (-)
C3H/HeJ MGP_C3HHeJ_G0025953
protein coding gene Chr2:106759698-106813609 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026654
protein coding gene Chr2:111660649-111700454 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024040
protein coding gene Chr2:99430077-99470153 (-)
CAST/EiJ MGP_CASTEiJ_G0025418
protein coding gene Chr2:107296416-107334639 (-)
CBA/J MGP_CBAJ_G0025931
protein coding gene Chr2:115553796-115593828 (-)
DBA/2J MGP_DBA2J_G0026069
protein coding gene Chr2:103195038-103233870 (-)
FVB/NJ MGP_FVBNJ_G0026032
protein coding gene Chr2:102159360-102197923 (-)
LP/J MGP_LPJ_G0026172
protein coding gene Chr2:108313740-108353384 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026056
protein coding gene Chr2:119395004-119432727 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026708
protein coding gene Chr2:106656803-106698415 (-)
PWK/PhJ MGP_PWKPhJ_G0025153
protein coding gene Chr2:102710710-102754923 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024953
protein coding gene Chr2:105901403-105941937 (-)
WSB/EiJ MGP_WSBEiJ_G0025485
protein coding gene Chr2:107392629-107431712 (-)



Homology
more
  • Human Ortholog
    DNAJC24, DnaJ heat shock protein family (Hsp40) member C24
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNAJC24, DnaJ heat shock protein family (Hsp40) member C24
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DPH4, JJJ3, ZCSL3
  • Links
    NCBI Gene ID: 120526
    neXtProt AC: NX_Q6P3W2
    UniProt: Q6P3W2

  • Chr Location
    11p13; chr11:31369829-31432835 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation are retarded in growth and development, and generally die before birth; those that survive long enough to initiate digit formation show a distinctive polydactyly phenotype on their hind limbs.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027166 Ensembl Gene Model | MGI Sequence Detail 36841 C57BL/6J ±  kb
    transcript ENSMUST00000102555 Ensembl | MGI Sequence Detail 1197 Not Applicable  
    polypeptide ENSMUSP00000099615 Ensembl | MGI Sequence Detail 148 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1916468, MGI:2139244, MGI:2139332
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    05/22/2019
    MGI 6.14
    The Jackson Laboratory