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Scaf11 Gene Detail
Summary
  • Symbol
    Scaf11
  • Name
    SR-related CTD-associated factor 11
  • Synonyms
    1110061H03Rik, 2610510E10Rik, CASP11, Sfrs2ip, SIP1, SRRP129, Srsf2ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919443
    NCBI Gene: 72193
  • Gene Overview
    MyGene.info: SCAF11
Location & Maps
more
  • Sequence Map
    Chr15:96411698-96460843 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      49146 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 52.44 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP
  • Links
    NCBI Gene ID: 9169
    neXtProt AC: NX_Q99590

  • Chr Location
    12q12; chr12:45919131-45992040 (-)  GRCh38.p2
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotype references
  • All Mutations and Alleles
    56
  • Chemically induced (other)
    1
  • Gene trapped
    50
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Scaf11
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    37
  • Tissues
    4
  • cDNA Data
    14
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72193 NCBI Gene Model | MGI Sequence Detail 49146 C57BL/6J ±  kb
transcript NM_028148 RefSeq | MGI Sequence Detail 7724 Not Specified  
polypeptide NP_082424 RefSeq | MGI Sequence Detail 1456 Not Specified  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    153 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 8
Other
Accession IDs
less
MGI:1916069, MGI:2146022
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 28
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:206632 Roberts JM, et al., Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol. 2014 Feb 1;522(2):372-92
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory