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Scaf11 Gene Detail
Summary
  • Symbol
    Scaf11
  • Name
    SR-related CTD-associated factor 11
  • Synonyms
    1110061H03Rik, 2610510E10Rik, CASP11, Sfrs2ip, SIP1, SRRP129, Srsf2ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919443
    NCBI Gene: 72193
  • Gene Overview
    MyGene.info: SCAF11
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96411699-96460843 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 52.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919443
protein coding gene Chr15:96411698-96460850 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022269
protein coding gene Chr15:97996725-98048051 (-)
A/J MGP_AJ_G0022228
protein coding gene Chr15:94160936-94209723 (-)
AKR/J MGP_AKRJ_G0022203
protein coding gene Chr15:96985942-97036040 (-)
BALB/cJ MGP_BALBcJ_G0022234
protein coding gene Chr15:94358415-94408324 (-)
C3H/HeJ MGP_C3HHeJ_G0022004
protein coding gene Chr15:97040031-97088963 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022679
protein coding gene Chr15:101624660-101675962 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020205
protein coding gene Chr15:90157606-90209081 (-)
CAST/EiJ MGP_CASTEiJ_G0021526
protein coding gene Chr15:97904183-97954820 (-)
CBA/J MGP_CBAJ_G0021971
protein coding gene Chr15:105004244-105058125 (-)
DBA/2J MGP_DBA2J_G0022098
protein coding gene Chr15:93605482-93654274 (-)
FVB/NJ MGP_FVBNJ_G0022077
protein coding gene Chr15:92590150-92639899 (-)
LP/J MGP_LPJ_G0022169
protein coding gene Chr15:98119581-98168413 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022097
protein coding gene Chr15:109216124-109274426 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022694
protein coding gene Chr15:97117441-97167660 (-)
PWK/PhJ MGP_PWKPhJ_G0021267
protein coding gene Chr15:93681249-93730680 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021101
protein coding gene Chr15:96911498-96963808 (-)
WSB/EiJ MGP_WSBEiJ_G0021575
protein coding gene Chr15:97631395-97682429 (-)



Homology
more
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP
  • Links
    NCBI Gene ID: 9169
    neXtProt AC: NX_Q99590
    UniProt: Q99590

  • Chr Location
    12q12; chr12:45919131-45992040 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033228 Ensembl Gene Model | MGI Sequence Detail 49145 C57BL/6J ±  kb
transcript ENSMUST00000047835 Ensembl | MGI Sequence Detail 5766 Not Applicable  
polypeptide ENSMUSP00000044898 Ensembl | MGI Sequence Detail 1456 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR027370 RING-type zinc-finger, LisH dimerisation motif
    IPR018957 Zinc finger, C3HC4 RING-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 8
Other
Accession IDs
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MGI:1916069, MGI:2146022
References
more
  • Summaries
    All 53
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 29
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory