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Scaf11 Gene Detail
Summary
  • Symbol
    Scaf11
  • Name
    SR-related CTD-associated factor 11
  • Synonyms
    1110061H03Rik, 2610510E10Rik, CASP11, Sfrs2ip, SIP1, SRRP129, Srsf2ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919443
    NCBI Gene: 72193
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96309580-96358695 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 52.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1171 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919443
 protein coding gene Chr15:96309580-96358724 (-)
129S1/SvImJ ENSMUSG00200046837
 protein coding gene Chr15:93511576-93544511 (-)
A/J ENSMUSGG00195055394
 protein coding gene Chr15:93372639-93398412 (-)
AKR/J ENSMUSG00220044197
 protein coding gene Chr15:93365575-93398514 (-)
BALB/cJ ENSMUSGG00180055494
 protein coding gene Chr15:93290237-93316006 (-)
C3H/HeJ ENSMUSGG00175055093
 protein coding gene Chr15:93552954-93578727 (-)
C57BL/6NJ ENSMUSG00215049642
 protein coding gene Chr15:93345992-93378925 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020205
 protein coding gene Chr15:90157606-90209081 (-)
CAST/EiJ ENSTCUG00005045326
 protein coding gene Chr15:92829857-92862837 (-)
CBA/J ENSMUSG00210030843
 protein coding gene Chr15:93325530-93358471 (-)
DBA/2J ENSMUSGG00185057383
 protein coding gene Chr15:93382903-93408679 (-)
FVB/NJ ENSMUSG00205043682
 protein coding gene Chr15:93086257-93119188 (-)
JF1/MsJ ENSUMUG00000045096
 protein coding gene Chr15:92869500-92902224 (-)
LP/J ENSMUSG00230032066
 protein coding gene Chr15:96691261-96724192 (-)
NOD/ShiLtJ ENSMUSGG00190055064
 protein coding gene Chr15:93390530-93416304 (-)
NZO/HlLtJ ENSMUSG00225041303
 protein coding gene Chr15:96991588-97024519 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010045093
 protein coding gene Chr15:94853241-94900430 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
  • Synonyms
    CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP
  • Links
    NCBI Gene ID: 9169
    UniProt: Q99590

  • Chr Location
    12q12; chr12:45919131-45992120 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    37 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    635
  • Tissues
    5
  • cDNA Data
    15
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72193 NCBI Gene Model | MGI Sequence Detail 49116 C57BL/6J ±  kb
    transcript NM_001402910 RefSeq | MGI Sequence Detail 7739 C57BL/6  
    polypeptide NP_001389839 RefSeq | MGI Sequence Detail 1472 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • InterPro Domains
      IPR057031 SFR19-like, C-terminal domain
      IPR018957 Zinc finger, C3HC4 RING-type
      IPR013083 Zinc finger, RING/FYVE/PHD-type
      IPR001841 Zinc finger, RING-type
      IPR017907 Zinc finger, RING-type, conserved site
      IPR027370 Zinc finger, RING-type, eukaryotic
    • GlyGen
      E9PZM7 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916069, MGI:2146022
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 3
      Phenotypes 37
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory