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Scaf11 Gene Detail
Summary
  • Symbol
    Scaf11
  • Name
    SR-related CTD-associated factor 11
  • Synonyms
    1110061H03Rik, 2610510E10Rik, CASP11, Sfrs2ip, SIP1, SRRP129, Srsf2ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919443
    NCBI Gene: 72193
  • Gene Overview
    MyGene.info: SCAF11
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96411699-96460843 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 52.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919443
protein coding gene Chr15:96411698-96460850 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022269
protein coding gene Chr15:97996725-98048051 (-)
A/J MGP_AJ_G0022228
protein coding gene Chr15:94160936-94209723 (-)
AKR/J MGP_AKRJ_G0022203
protein coding gene Chr15:96985942-97036040 (-)
BALB/cJ MGP_BALBcJ_G0022234
protein coding gene Chr15:94358415-94408324 (-)
C3H/HeJ MGP_C3HHeJ_G0022004
protein coding gene Chr15:97040031-97088963 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022679
protein coding gene Chr15:101624660-101675962 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020205
protein coding gene Chr15:90157606-90209081 (-)
CAST/EiJ MGP_CASTEiJ_G0021526
protein coding gene Chr15:97904183-97954820 (-)
CBA/J MGP_CBAJ_G0021971
protein coding gene Chr15:105004244-105058125 (-)
DBA/2J MGP_DBA2J_G0022098
protein coding gene Chr15:93605482-93654274 (-)
FVB/NJ MGP_FVBNJ_G0022077
protein coding gene Chr15:92590150-92639899 (-)
LP/J MGP_LPJ_G0022169
protein coding gene Chr15:98119581-98168413 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022097
protein coding gene Chr15:109216124-109274426 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022694
protein coding gene Chr15:97117441-97167660 (-)
PWK/PhJ MGP_PWKPhJ_G0021267
protein coding gene Chr15:93681249-93730680 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021101
protein coding gene Chr15:96911498-96963808 (-)
WSB/EiJ MGP_WSBEiJ_G0021575
protein coding gene Chr15:97631395-97682429 (-)



Homology
more
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SCAF11, SR-related CTD associated factor 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP
  • Links
    NCBI Gene ID: 9169
    neXtProt AC: NX_Q99590
    UniProt: Q99590

  • Chr Location
    12q12; chr12:45919131-45992040 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033228 Ensembl Gene Model | MGI Sequence Detail 49145 C57BL/6J ±  kb
    transcript ENSMUST00000047835 Ensembl | MGI Sequence Detail 5766 Not Applicable  
    polypeptide ENSMUSP00000044898 Ensembl | MGI Sequence Detail 1456 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • InterPro Domains
      IPR027370 RING-type zinc-finger, LisH dimerisation motif
      IPR018957 Zinc finger, C3HC4 RING-type
      IPR013083 Zinc finger, RING/FYVE/PHD-type
      IPR001841 Zinc finger, RING-type
      IPR017907 Zinc finger, RING-type, conserved site
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916069, MGI:2146022
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 1
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory