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Zfp157 Gene Detail
Summary
  • Symbol
    Zfp157
  • Name
    zinc finger protein 157
  • Synonyms
    2610020C11Rik, A630094N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919404
    NCBI Gene: 72154
Location & Maps
more
  • Sequence Map
    Chr5:138441468-138460694 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19227 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 77.09 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZNF613, zinc finger protein 613
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZNF613, zinc finger protein 613
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 79898
    neXtProt AC: NX_Q6PF04

  • Chr Location
    19q13.41; chr19:51927147-51945758 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Gene trapped
    6
  • Targeted
    2
  • Incidental Mutations
    APF
Mice homozygous for a null allele display accelerated ductal elongation during puberty and accelerated alveologenesis during pregnancy.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022795 VEGA Gene Model | MGI Sequence Detail 19227 C57BL/6J ±  kb
transcript OTTMUST00000054762 VEGA | MGI Sequence Detail 5312 Not Applicable  
polypeptide OTTMUSP00000026164 VEGA | MGI Sequence Detail 567 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    262 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR001909 Krueppel-associated box
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140848, MGI:2444101
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194068 Oliver CH, et al., The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin. Genesis. 2013 Mar;51(3):179-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory