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Rfc5 Gene Detail
Summary
  • Symbol
    Rfc5
  • Name
    replication factor C (activator 1) 5
  • Synonyms
    2610020K06Rik, 2610209F07Rik, 36.5kDa, 36kDa, Recc5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919401
    NCBI Gene: 72151
  • Gene Overview
    MyGene.info: RFC5
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:117379145-117389023 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 56.88 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919401
protein coding gene Chr5:117378103-117389047 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029988
protein coding gene Chr5:120464895-120477172 (-)
A/J MGP_AJ_G0029952
protein coding gene Chr5:115562013-115572640 (-)
AKR/J MGP_AKRJ_G0029891
protein coding gene Chr5:119298567-119309145 (-)
BALB/cJ MGP_BALBcJ_G0029963
protein coding gene Chr5:116981483-116992110 (-)
C3H/HeJ MGP_C3HHeJ_G0029683
protein coding gene Chr5:119815355-119825926 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030418
protein coding gene Chr5:125045222-125056160 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027644
protein coding gene Chr5:110322004-110332841 (-)
CAST/EiJ MGP_CASTEiJ_G0029092
protein coding gene Chr5:118821629-118832404 (-)
CBA/J MGP_CBAJ_G0029651
protein coding gene Chr5:129870740-129882399 (-)
DBA/2J MGP_DBA2J_G0029801
protein coding gene Chr5:115661077-115671620 (-)
FVB/NJ MGP_FVBNJ_G0029757
protein coding gene Chr5:114524775-114535399 (-)
LP/J MGP_LPJ_G0029889
protein coding gene Chr5:120962712-120973661 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029788
protein coding gene Chr5:134089809-134100431 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030459
protein coding gene Chr5:118824193-118835120 (-)
PWK/PhJ MGP_PWKPhJ_G0028805
protein coding gene Chr5:114353371-114364404 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028643
protein coding gene Chr5:116386929-116397720 (-)
WSB/EiJ MGP_WSBEiJ_G0029167
protein coding gene Chr5:119393489-119406200 (-)



Homology
more
  • Human Ortholog
    RFC5, replication factor C subunit 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RFC5, replication factor C subunit 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RFC36
  • Links
    NCBI Gene ID: 5985
    neXtProt AC: NX_P40937
    UniProt: P40937

  • Chr Location
    12q24.23; chr12:118016701-118033568 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Rfc5
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 72151 NCBI Gene Model | MGI Sequence Detail 9879 C57BL/6J ±  kb
transcript NM_028128 RefSeq | MGI Sequence Detail 1750 C57BL/6  
polypeptide Q9D0F6 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013909 replication factor C subunit 5
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003959 ATPase, AAA-type, core
    IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013748 Replication factor C, C-terminal
Molecular
Reagents
less
  • All nucleic 85
    cDNA 85

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13829, MGI:1924040, MGI:97894
References
more
  • Summaries
    All 39
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:202812 Vannier JB, et al., RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science. 2013 Oct 11;342(6155):239-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory