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Strada
Gene Detail
Symbol

Name
ID
Strada
STE20-related kinase adaptor alpha
MGI:1919399
Synonyms
2610019A05Rik, 6030402H20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
68.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:106163330-106202168 bp, - strand
From VEGA annotation of GRCm38

  38839 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12448  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STRADA
Protein SuperFamily: STE20-related adapter protein
Gene Tree: Strada

Human
homologs
STRADA, STE20-related kinase adaptor alpha
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 92335
neXtProt AC: NX_Q7RTN6

Human Synonyms: LYK5, NY-BR-96, PMSE, Stlk, STRAD

Human Chr (Location): 17q23.3; chr17:63702832-63741970 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human STRADA

Mutations,
alleles, and
phenotypes
All mutations/alleles(76) : Gene trapped(73) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Strada interacts with 308 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process actin cytoskeleton organization, activation of protein kinase activity, ...
Component cytoplasm, nucleoplasm, ...
Function ATP binding, kinase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (9)    Tissues (5)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 5
cDNA source data(59)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase strada ; ZFIN strada    NEW 
Molecular
reagents
All nucleic(60) cDNA(60)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000003220 (Evidence)
Ensembl Gene Model ENSMUSG00000069631 (Evidence)
Entrez Gene 72149 (Evidence)
UniGene 403722
DFCI TC1691484, TC1578907, TC1597938, TC1596138, TC1678513
NIA Mouse Gene Index U033536
Consensus CDS Project CCDS25550.1, CCDS56816.1
International Mouse Phenotyping Consortium Status Strada
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003220 VEGA Gene Model | MGI Sequence Detail 38839 C57BL/6J ±  kb
transcript OTTMUST00000006681 VEGA | MGI Sequence Detail 2099 Not Applicable 
polypeptide OTTMUSP00000003174 VEGA | MGI Sequence Detail 431 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(18) UniProt(4)
Polymorphisms
SNPs within 2kb(123 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000015774 STE20-related kinase adapter protein alpha
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:207603 Veleva-Rotse BO, et al., STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5
All references(39)
Other
accession IDs
MGI:2144190, MGI:2443040

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory