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Pygo1 Gene Detail
Summary
  • Symbol
    Pygo1
  • Name
    pygopus 1
  • Synonyms
    2600014C22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919385
    NCBI Gene: 72135
  • Gene Overview
    MyGene.info: PYGO1
Location & Maps
more
  • Sequence Map
    Chr9:72925645-72952181 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26537 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 40.08 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PYGO1, pygopus family PHD finger 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PYGO1, pygopus family PHD finger 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 26108
    neXtProt AC: NX_Q9Y3Y4
    UniProt: Q9Y3Y4

  • Chr Location
    15q21.3; chr15:55538884-55588852 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41050
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PYGO1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotypes from multigenic genotypes
    1 images
    9 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    6
  • Genomic Mutations
    1 involving Pygo1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Homozygous null mice are viable and show no obvious phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027456 VEGA Gene Model | MGI Sequence Detail 26537 C57BL/6J ±  kb
transcript OTTMUST00000067939 VEGA | MGI Sequence Detail 7916 Not Applicable  
polypeptide OTTMUSP00000034265 VEGA | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    82 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 41
    Developmental Gene Expression 9
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213694 Cantu C, et al., Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes Dev. 2014 Sep 1;28(17):1879-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
03/14/2017
MGI 6.08
The Jackson Laboratory