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Pex13
Gene Detail
 Symbol
Name
ID
Pex13
peroxisomal biogenesis factor 13
MGI:1919379
Synonyms 2610008O20Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
14.34 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:23646479-23665959 bp, - strand
From VEGA annotation of GRCm38

  19481 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1967  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Pex13

Human
homologs
Human Homolog PEX13, peroxisomal biogenesis factor 13
NCBI Gene ID 5194
neXtProt AC  NX_Q92968
Human Synonyms  NALD, PBD11A, PBD11B, ZWS
Human Chr (Location)  2p16.1; chr2:61017677-61051990 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human PEX13
Alleles
and
phenotypes
All alleles(43) : Targeted(4) Gene trapped(39)
 
Targeted disruption of this gene results in intrauterine growth retardation, hypotonia, aphagia, abnormal lamination of the cerebral cortex associated with a neuronal migration defect, liver steatosis, delayed differentiation of renal glomeruli, impaired peroxisome metabolism, and neonatal death.
 
Human Diseases Modeled Using Mouse Pex13 (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cerebral cortex cell migration, fatty acid alpha-oxidation, ...
Component integral component of membrane, integral component of peroxisomal membrane, ...
Function peroxisome targeting sequence binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000005277 (Evidence)
Ensembl Gene ModelENSMUSG00000020283 (Evidence)
Entrez Gene72129 (Evidence)
DFCITC1574980, TC1623942, TC1638560, TC1671980
DoTSDT.101390341, DT.492127, DT.91419960
NIA Mouse Gene IndexU032575
PDB1WXU
Consensus CDS ProjectCCDS24478.1
International Mouse Knockout Project StatusPex13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005277 VEGA Gene Model | MGI Sequence Detail 19481 C57BL/6J ±  kb
transcript OTTMUST00000011762 VEGA | MGI Sequence Detail 4146 Not Applicable 
polypeptide OTTMUSP00000005454 VEGA | MGI Sequence Detail 405 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(23 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007223 Peroxin 13, N-terminal
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000012559 peroxisomal membrane protein PEX13
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory