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Amer2 Gene Detail
Summary
  • Symbol
    Amer2
  • Name
    APC membrane recruitment 2
  • Synonyms
    2600011E07Rik, Amer2, Fam123a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919375
    NCBI Gene: 72125
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:60373297-60388197 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 31.62 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    63 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919375
protein coding gene Chr14:60373259-60388197 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021432
protein coding gene Chr14:54717639-54720355 (+)
A/J MGP_AJ_G0021391
protein coding gene Chr14:53528265-53530976 (+)
AKR/J MGP_AKRJ_G0021366
protein coding gene Chr14:55431804-55434515 (+)
BALB/cJ MGP_BALBcJ_G0021396
protein coding gene Chr14:53493037-53495745 (+)
C3H/HeJ MGP_C3HHeJ_G0021174
protein coding gene Chr14:55099546-55102262 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021835
protein coding gene Chr14:57396344-57399061 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019375
protein coding gene Chr14:51562276-51564971 (+)
CAST/EiJ MGP_CASTEiJ_G0020690
protein coding gene Chr14:51485332-51488043 (+)
CBA/J MGP_CBAJ_G0021141
protein coding gene Chr14:59044531-59047242 (+)
DBA/2J MGP_DBA2J_G0021264
protein coding gene Chr14:53206486-53209202 (+)
FVB/NJ MGP_FVBNJ_G0021242
protein coding gene Chr14:52623044-52625760 (+)
LP/J MGP_LPJ_G0021338
protein coding gene Chr14:55758183-55760899 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021271
protein coding gene Chr14:58410347-58413166 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021858
protein coding gene Chr14:54589702-54592418 (+)
PWK/PhJ MGP_PWKPhJ_G0020434
protein coding gene Chr14:49862025-49864838 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020267
protein coding gene Chr14:50552871-50555570 (+)
WSB/EiJ MGP_WSBEiJ_G0020743
protein coding gene Chr14:54906817-54909577 (+)



Homology
more
  • Human Ortholog
    AMER2, APC membrane recruitment protein 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    AMER2, APC membrane recruitment protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FAM123A
  • Links
    NCBI Gene ID: 219287
    neXtProt AC: NX_Q8N7J2
    UniProt: Q8N7J2

  • Chr Location
    13q12.13; chr13:25161679-25172456 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 72125 NCBI Gene Model | MGI Sequence Detail 14901 C57BL/6J ±  kb
transcript NM_028113 RefSeq | MGI Sequence Detail 2718 C57BL/6  
polypeptide Q8CCJ4 UniProt | EBI | MGI Sequence Detail 672 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR019003 APC membrane recruitment protein
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory