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Dscc1
Gene Detail
Symbol

Name
ID
Dscc1
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
MGI:1919357
Synonyms
2010006I05Rik, 2600005O03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 15
21.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:55076099-55090491 bp, - strand
From VEGA annotation of GRCm38

  14393 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5464  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DSCC1
Gene Tree: Dscc1

Human
homologs
DSCC1, DNA replication and sister chromatid cohesion 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 79075
neXtProt AC: NX_Q9BVC3

Human Synonyms: DCC1

Human Chr (Location): 8q24.12; chr8:119833941-119855930 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dscc1 interacts with 28 markers (Mir103-1, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell cycle, DNA replication, ...
Component chromatin, chromosome, centromeric region, ...
Function DNA binding, DNA clamp loader activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (42)    Tissues (7)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dscc1 ; ZFIN dscc1    NEW 
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023435 (Evidence)
Ensembl Gene Model ENSMUSG00000022422 (Evidence)
Entrez Gene 72107 (Evidence)
UniGene 486550
DFCI TC1606043, TC1584129
DoTS DT.110835768, DT.55182955, DT.94164107
NIA Mouse Gene Index U036177
Consensus CDS Project CCDS27473.1
International Mouse Phenotyping Consortium Status Dscc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023435 VEGA Gene Model | MGI Sequence Detail 14393 C57BL/6J ±  kb
transcript OTTMUST00000056962 VEGA | MGI Sequence Detail 1499 Not Applicable 
polypeptide OTTMUSP00000027433 VEGA | MGI Sequence Detail 462 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019128 Sister chromatid cohesion protein Dcc1
Protein Ontology PR:000006697 sister chromatid cohesion protein DCC1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:1917089

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory